Evidence map›Paper›PMID 1468113›Full record

ReviewCellular and molecular neurobiology1992

Invertebrate and vertebrate neuroimmune and autoimmunoregulatory commonalties involving opioid peptides.

G B Stefano

Open access · greenAbstract readReview
In one paragraph

Review in Cellular and molecular neurobiology, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.4field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 39 citations in OpenAlex.

  1. Cognition Regulated by Emotional Decision Making.Medical science monitor basic research · 2016
    Article
  2. Hypoxia defined as a common culprit/initiation factor in mitochondrial-mediated proinflammatory processes.Medical science monitor : international medical journal of experimental and clinical research · 2015
    Review
  3. Microglia in invertebrate ganglia.Proceedings of the National Academy of Sciences of the United States of America · 1994
    Article
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

G B StefanoMultidisciplinary Center for the Study of Aging, State University of New York, Old Westbury 11568-0210.
SUNY Old Westbury · US

Funding

NIMH COR HONORS UNDERGRADUATE RESEARCH TRAININGT34MH017138 · NIMH · COLLEGE AT OLD WESTBURY · PI PRYOR, STEPHEN CARL · 1985 to 2008
$1.4M
NIDA NIH HHS DA 47392NIMH NIH HHS MH 17138
6 · The paper itself

Abstract

1. Evidence for bidirectional interrelationships between the nervous system and immune systems of vertebrates and invertebrates involving opioid peptides is briefly discussed. 2. The involvement of opioid peptides in autoimmunoregulatory communication also is discussed. 3. The presence of mammalian interleukin-like (1 & 6) and tumor necrosis factor-like molecules in invertebrates is reviewed as well as an apparent cascading system for these signal molecules. 4. The significance of ACTH and MSH in cellular immunosuppression and autoimmunoregulation is discussed in the context of a potential role in schistosomiasis and human immunodeficiency virus actions. 5. The review concludes with the hypothesis that the mammalian immune system has its origin in the invertebrate immune/defense system given the many similarities noted in the review based on new knowledge about the more "primitive" system.

Indexed as

AutoimmunityNeuroimmunomodulationAnimalsBiological EvolutionEndorphinsImmune SystemInvertebratesModels, BiologicalNervous System Physiological PhenomenaNeuropeptidesSignal TransductionVertebratesEndorphinsNeuropeptides

Identifiers

PMID1468113
PMCPMC11567414
OpenAlexW2013900260

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.