ArticleBreast cancer research : BCR2004
Expression of androgen receptor and prostate-specific antigen in male breast carcinoma.
Article in Breast cancer research : BCR, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 70 citations in OpenAlex.
- Metastases to the Male Breast: A Systematic Review.Cancers · 2026Review
- Host versus cell-dependent effects of β-arrestin 1 expression in prostate tumorigenesis.Carcinogenesis · 2021Article
- Reconnoitring the status of prostate specific antigen and its role in women.Indian journal of clinical biochemistry : IJCB · 2015Review
- Breast cancer: trends in international incidence in men and women.British journal of cancer · 2014Article
- Male breast carcinoma: a clinicopathological and immunohistochemical characterization study.International journal of clinical and experimental pathology · 2014Article
- [Breast cancer in men: about 6 cases].The Pan African medical journal · 2013Article
- Lobular Breast Cancer in a Male Patient with a Previous History of Irradiation Due to Hodgkin's Disease.Breast care (Basel, Switzerland) · 2012Article
- Long CAG repeat sequence and protein expression of androgen receptor considered as prognostic indicators in male breast carcinoma.PloS one · 2012Article
- Intracystic Papillary Carcinoma of the Breast in Males. In Search of the Optimal Treatment for this Rare Disease.Breast care (Basel, Switzerland) · 2011Article
- Prostatic acid phosphatase expression in human tissues.International journal of clinical and experimental pathology · 2011Article
- Prostate-specific antigen and hormone receptor expression in male and female breast carcinoma.Diagnostic pathology · 2010Article
- Mucinous breast carcinoma presenting as Paget's disease of the nipple in a man: a case report.Diagnostic pathology · 2008Article
- Prolactin drives estrogen receptor-alpha-dependent ductal expansion and synergizes with transforming growth factor-alpha to induce mammary tumors in males.The American journal of pathology · 2008Article
- The histological diagnosis of metastases to the breast from extramammary malignancies.Journal of clinical pathology · 2007Review
- Expression of prostate specific antigen in male breast cancer.Journal of clinical pathology · 2005Article
- Prostate Cancer: Cases of Rare Presentation and Rare Metastasis.Case reports in oncologyArticle
- Male Breast Cancer.Breast care (Basel, Switzerland)Article
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7 authors at 2 institutions in 1 country.
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Abstract
backgroundThe androgen-regulated proteins prostate-specific antigen (PSA) and prostate-specific acid phosphatase (PSAP) are present in high concentrations in normal prostate and prostatic cancer and are considered to be tissue-specific to prostate. These markers are commonly used to diagnose metastatic prostate carcinoma at various sites including the male breast. However, expression of these two proteins in tumors arising in tissues regulated by androgens such as male breast carcinoma has not been thoroughly evaluated.
methodsIn this study we analyzed the expression of PSA, PSAP and androgen receptor (AR) by immunohistochemistry in 26 cases of male breast carcinomas and correlated these with the expression of other prognostic markers.
resultsAR, PSA and PSAP expression was observed in 81%, 23% and 0% of carcinomas, respectively. Combined expression of AR and PSA was observed in only four tumors.
conclusionAlthough the biological significance of PSA expression in male breast carcinomas is not clear, caution should be exercised when it is used as a diagnostic marker of metastatic prostate carcinoma.
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