ArticleEcotoxicology (London, England)2003
Proteomics in zebrafish exposed to endocrine disrupting chemicals.
Article in Ecotoxicology (London, England), 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Phospholipid isotope tracing suggests β-catenin-driven suppression of phosphatidylcholine metabolism in hepatocellular carcinoma.Biochimica et biophysica acta. Molecular and cell biology of lipids · 2024Article
- Phospholipid isotope tracing reveals β-catenin-driven suppression of phosphatidylcholine metabolism in hepatocellular carcinoma.bioRxiv : the preprint server for biology · 2023Article
- Effects of Bisphenol A on redox balance in red blood and sperm cells and spermatic quality in zebrafish Danio rerio.Ecotoxicology (London, England) · 2019Article
- Tools to minimize interlaboratory variability in vitellogenin gene expression monitoring programs.Environmental toxicology and chemistry · 2017Article
- Evaluation and Comparison of Four Protein Extraction Protocols for Mono- and Two-Dimensional Electrophoresis inItalian journal of food safety · 2015Article
- Ecotoxicogenomic approaches for understanding molecular mechanisms of environmental chemical toxicity using aquatic invertebrate, Daphnia model organism.International journal of molecular sciences · 2015Review
- Finding biomarkers is getting easier.Ecotoxicology (London, England) · 2012Review
- DIGE and iTRAQ as biomarker discovery tools in aquatic toxicology.Ecotoxicology and environmental safety · 2012Review
- Peptide biomarkers as evidence of perchlorate biodegradation.Applied and environmental microbiology · 2011Article
- A reference growth curve for nutritional experiments in zebrafish (Danio rerio) and changes in whole body proteome during development.Fish physiology and biochemistry · 2010Article
- Article
- Proteomic Signatures of the Zebrafish (Danio rerio) Embryo: Sensitivity and Specificity in Toxicity Assessment of Chemicals.International journal of proteomics · 2010Article
- Protein expression profiling in the African clawed frog Xenopus laevis tadpoles exposed to the polychlorinated biphenyl mixture aroclor 1254.Molecular & cellular proteomics : MCP · 2009Article
- Hepatic and extrahepatic expression of estrogen-responsive genes in male adult zebrafish (Danio rerio) as biomarkers of short-term exposure to 17beta-estradiol.Environmental monitoring and assessment · 2008Article
- The zebrafish embryo model in environmental risk assessment--applications beyond acute toxicity testing.Environmental science and pollution research international · 2008Review
- Data processing and classification analysis of proteomic changes: a case study of oil pollution in the mussel, Mytilus edulis.Proteome science · 2006Article
- Toxicogenomics in regulatory ecotoxicology.Environmental science & technology · 2006Article
- Proteomics of early zebrafish embryos.BMC developmental biology · 2006Article
- Proteomic analysis of cadmium-induced protein profile alterations from marine alga Nannochloropsis oculata.Ecotoxicology (London, England) · 2005Article
- The dorsal diencephalic conduction system of zebrafish as a model of vertebrate brain lateralisation.Neuroreport · 2004Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Embryonic zebrafish were examined for changes in protein expression following exposure to sublethal concentrations of 17beta-estradiol (E2) and the estrogen mimic 4-nonylphenol (4-NP). Protein Expression Signatures were derived from embryo homogenates by two-dimensional electrophoresis and digital imaging. In both experiments approximately 30% of the proteins sampled were specific to either E2 or 4-NP and about 33% were common to the control, 4-NP and E2. However, of the proteins induced by either E2 or 4-NP, 28% were common to both chemicals at 1 ppm but only 7% were common to both at 0.1 ppm. While there are many proteins that respond specifically to each chemical, relatively few are common to the two chemicals suggesting that the response pathways of the two chemicals are distinct.
Indexed as
Identifiers
14680328What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.