Evidence map›Paper›PMID 14679243›Full record

ArticleJournal of bacteriology2004

Null mutation of HvrA compensates for loss of an essential relA/spoT-like gene in Rhodobacter capsulatus.

Shinji Masuda, Carl E Bauer

Open access · greenAbstract read
In one paragraph

Article in Journal of bacteriology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 48 citations in OpenAlex.

  1. Article
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  10. Regulation of stringent factor by branched-chain amino acids.Proceedings of the National Academy of Sciences of the United States of America · 2018
    Article
  11. Review
  12. The Vitamin BmBio · 2017
    Article
  13. Review
  14. Sulfide-responsive transcriptional repressor SqrR functions as a master regulator of sulfide-dependent photosynthesis.Proceedings of the National Academy of Sciences of the United States of America · 2017
    Article
  15. The stringent response regulates adaptation to darkness in the cyanobacterium Synechococcus elongatus.Proceedings of the National Academy of Sciences of the United States of America · 2016
    Article
  16. Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Shinji MasudaLaboratory for Photobiology, RIKEN Photodynamics Research Center, Sendai 980-0845, Japan. smasuda@postman.riken.go.jp
Carl E Bauer
Indiana University Bloomington · USRIKEN Center for Advanced Photonics · JP

Funding

Prokaryotic gene regulation by light and oxygenR37GM040941 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI BAUER, CARL EUGENE · 2006 to 2016
$5.4M
PROKARYOTIC GENE REGULATION BY LIGHT AND OXYGENR01GM040941 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI BAUER, CARL EUGENE · 1994 to 2020
$3.3M
NIGMS NIH HHS R01 GM040941NIGMS NIH HHS R37 GM040941
6 · The paper itself

Abstract

We report that a single relA/spoT-like gene exists on the Rhodobacter capsulatus chromosome, and its mutational loss is lethal. This gene could be mutated only under a mutational background of a null mutation in the nucleoid protein HvrA. This result suggests that there may be a direct link between HvrA-regulated promoters and the ppGpp-related stringent response.

Indexed as

Amino Acid SequenceBacterial ProteinsCulture MediaGene Expression Regulation, BacterialGuanosine TetraphosphateMolecular Sequence DataMutationNF-kappa BPigments, BiologicalPyrophosphatasesRhodobacter capsulatusTrans-ActivatorsTranscription Factor RelABacterial ProteinsCulture Mediaguanosine-3',5'-bis(diphosphate) 3'-pyrophosphataseGuanosine TetraphosphateHvrA protein, Rhodobacter capsulatusNF-kappa BPigments, BiologicalPyrophosphatasesTrans-ActivatorsTranscription Factor RelA

Identifiers

PMID14679243
PMCPMC303453
OpenAlexW2104002563

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.