Evidence map›Paper›PMID 14679172›Full record

ArticleThe Journal of clinical investigation2003

Obesity-induced inflammatory changes in adipose tissue.

Kathryn E Wellen, Gokhan S Hotamisligil

Abstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of clinical investigation, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 656 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
656citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

656 citing papers in PubMed, 5 syntheses or guidelines pooled it.

  1. Pooled it
  2. Is Obesity a Risk Factor for Periodontal Disease in Adults? A Systematic Review.International journal of environmental research and public health · 2022
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  8. The effects of fish oil plus vitamin DEuropean journal of nutrition · 2022
    Trial
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596 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Kathryn E WellenDepartment of Genetics and Complex Diseases, Harvard School Of Public Health, 665 Huntington Avenue, Boston, Massachusetts 02115, USA.
Gokhan S Hotamisligil

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obesity is associated with a state of chronic, low-grade inflammation. Two manuscripts in this issue of the JCI (see the related articles beginning on pages 1796 and 1821) now report that obese adipose tissue is characterized by macrophage infiltration and that these macrophages are an important source of inflammation in this tissue. These studies prompt consideration of new models to include a major role for macrophages in the molecular changes that occur in adipose tissue in obesity.

Indexed as

InflammationObesityAdipose TissueAnimalsBiological EvolutionDiabetes Mellitus, Type 2HumansMacrophagesModels, BiologicalTranscription, Genetic

Identifiers

PMID14679172
PMCPMC297006

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.