Evidence map›Paper›PMID 14676776›Full record

ArticleBone marrow transplantation2004

Autologous stem cell transplantation in adult patients with peripheral T-cell lymphoma: a nation-wide survey.

E Jantunen, T Wiklund, E Juvonen, M Putkonen, T Lehtinen, O Kuittinen, K Franssila, K-O Söderström, S Leppä, E Elonen and 2 more

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Bone marrow transplantation, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 83 citations in OpenAlex.

  1. Favorable outcomes in elderly patients undergoing high-dose therapy and autologous stem cell transplantation for non-Hodgkin lymphoma.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2014
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  12. Peripheral T-cell lymphomas in a large US multicenter cohort: prognostication in the modern era including impact of frontline therapy.Annals of oncology : official journal of the European Society for Medical Oncology · 2014
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 1 country.

E JantunenDepartment of Medicine, Kuopio University Hospital, Kuopio, Finland. esa.jantunen@kuh.fi
T Wiklund
E Juvonen
M Putkonen
T Lehtinen
O Kuittinen
K Franssila
K-O Söderström
S Leppä
E Elonen
K Remes
T Nousiainen
Helsinki University Hospital · FIKuopio University Hospital · FITurku University Hospital · FIOulu University Hospital · FITampere University · FIUniversity of Turku · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Limited experience is available on the feasibility and efficacy of high-dose therapy (HDT) supported by autologous stem cell transplantation (ASCT) in patients with peripheral T-cell lymphoma (PTCL). Therefore, a nation-wide survey was conducted in adult patients transplanted for PTCL in Finland during 1990-2001. After histopathology review, 37 patients were identified. The median age was 46 years (16-68) at the time of ASCT. Histology included PTCL not otherwise specified in 14 patients, anaplastic large cell lymphoma (ALCL) in 14 patients, and other in nine patients. Disease status at the time of ASCT was CR/PR1 in 18 patients; CR/PR2 in 14 patients, and other in five patients. HDT consisted of either BEAC (N=22) or BEAM (N=15), supported by blood stem cells in 34 patients (92%). Early transplant-related mortality was 11%. With a median follow-up of 24 months from HDT, 16 patients (43%) have relapsed or progressed. The estimated 5-year overall survival (OS) was 54%. Patients with ALCL had superior OS when compared with other subtypes (85 vs 35%, P=0.007). OS at 5 years was 63% in patients transplanted in CR/PR1 vs 45% in those transplanted in other disease status (P=NS). Prospective studies are needed to define the role of ASCT in this lymphoma type.

Indexed as

AdolescentAdultAgedAntineoplastic Combined Chemotherapy ProtocolsBlood Component RemovalData CollectionFinlandFollow-Up StudiesHematopoietic Stem Cell TransplantationHumansLymphoma, T-Cell, PeripheralMiddle AgedRecurrenceRemission InductionSurvival AnalysisTransplantation, Autologous

Identifiers

PMID14676776
OpenAlexW2077779954

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.