ReviewJournal of clinical virology : the official publication of the Pan American Society for Clinical Virology2004
A role for arrays in clinical virology: fact or fiction?
Review in Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed.
- The Future of Gene Expression Studies in HIV Research.Current HIV research · 2025Review
- Comparison of the digene HPV genotyping LQ test and the PANArray HPV genotyping chip for detection of high-risk or probable high-risk human papillomavirus genotypes.Annals of laboratory medicine · 2014Article
- Metagenomics and the molecular identification of novel viruses.Veterinary journal (London, England : 1997) · 2011Review
- A technological update of molecular diagnostics for infectious diseases.Infectious disorders drug targets · 2008Review
- Transcriptional profile of red seabream iridovirus in a fish model as revealed by viral DNA microarrays.Virus genes · 2007Article
- Robust sequence selection method used to develop the FluChip diagnostic microarray for influenza virus.Journal of clinical microbiology · 2006Article
- Review
- Advances in viral respiratory infections: new experimental models.Drug discovery today. Disease models · 2004Review
- Molecular diagnostics in virology.Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology · 2004Article
- Real-time Fluorescent PCR Techniques to Study Microbial-Host Interactions.Methods in microbiology · 2004Review
- Virus discovery by sequence-independent genome amplification.Reviews in medical virologyReview
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Microarrays of DNA probes have at least three roles in clinical virology. These are: firstly, in diagnosis, to recognise the causative agent of an illness; secondly, for molecular typing for (i) patient management, (ii) epidemiological reasons (e.g. investigating routes of transmission), (iii) purposes related to vaccine use; and thirdly, in research, to investigate the interactions between the virus and the host cell. Microarrays intended for syndromic diagnostic purposes require genome specific probes to capture the unknown target viral sequences and thereby reveal the presence of that virus in a test sample. Microarrays intended for typing and patient management, e.g. monitoring antiviral drug resistant mutations require a set of probes representing the important sequence variants of one or more viral genes. Microarrays intended for research into virus-host interactions require probes representative of each individual gene or mRNA of either the virus or the host genome. Diagnostic microarrays are dependent for their utility and versatility on generic, multiplex or random polymerase chain reactions that will amplify any of several (unknown) viral target sequences from a patient sample. In this review, the existing and potential applications of microarrays in virology, and the problems that need to be overcome for future success, are discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.