Trial reportInternational journal of impotence research2003
Human glans penis augmentation using injectable hyaluronic acid gel.
Trial report in International journal of impotence research, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Clinical use of hyaluronic acid in andrology: A review.Andrology · 2022Pooled it
- Hyaluronic acid versus botulinum a toxin injection in the treatment of premature ejaculation: A comparative study.Scientific reports · 2025Trial
- Managing residual volumes in penile girth enhancement with hyaluronic acid fillers: a case series and literature review.International journal of impotence research · 2026Review
- Complications of penile augmentation: A narrative review of injectables, implants, and surgical grafts.International journal of impotence research · 2026Review
- Surgical treatment of premature ejaculation: a narrative review.International journal of impotence research · 2024Review
- Hyaluronic acid injection to coronal sulcus of the penis for the treatment of premature ejaculation: a retrospective observational study.BMC urology · 2023Observational
- The Application of Hyaluronic Acid Injections in Functional and Aesthetic Andrology: A Narrative Review.Gels (Basel, Switzerland) · 2023Review
- Glans penis augmentation: when, how, and why?International journal of impotence research · 2022Review
- Penile girth augmentation by injectable fillers: a comprehensive review of imaging features and inflammatory complications.Abdominal radiology (New York) · 2021Review
- Complications of glans penis augmentation.International journal of impotence research · 2019Review
- Practice Patterns Among Korean Urologists for Glans Penis Augmentation Using Hyaluronic Acid Filler in the Management of Premature Ejaculation.Sexual medicine · 2018Article
- Glans Penis Augmentation Using Hyaluronic Acid Gel as an Injectable Filler.The world journal of men's health · 2015Review
- The use of an acellular collagen matrix in penile augmentation: A pilot study in Saudi Arabia.Arab journal of urology · 2013Article
- A clinical study to assess the effectiveness of a hyaluronic acid-based procedure for treatment of premature ejaculation.International journal of impotence research · 2013Article
- Aesthetic surgery of the male genitalia.Seminars in plastic surgery · 2011Article
- Commentary on "Penile augmentation with injectable hyaluronic acid gel: an alternative choice for small penis syndrome".Asian journal of andrologyArticle
- Efficacy and safety of newly developed cross-linked dextran gel injection for glans penis augmentation with a novel technique.Asian journal of andrologyArticle
- Long-term effects of glans penis augmentation using injectable hyaluronic acid gel for premature ejaculation.International journal of impotence researchArticle
- Complications and management of penile augmentation with hyaluronic acid injection.Asian journal of andrologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Although augmentation phalloplasty is not an established procedure, some patients still need enlargement of their penis. Current penile augmentation is girth enhancement of penile body by dermofat graft. We performed this study to identify the efficacy and the patient's satisfaction of human glans penis augmentation with injectable hyaluronic acid gel. In 100 patients of subjective small penis (Group I) and 87 patients of small glans after dermofat graft (Group II), 2 cm(3) of hyaluronic acid gel was injected into the glans penis, subcutaneously. At 1 y after injection, changes of glandular diameter were measured by tapeline. Patient's visual estimation of glandular size (Gr 0-4) and patient's satisfaction (Grade (Gr) 0-4) were evaluated, respectively. Any adverse reactions were also evaluated. The mean age of patients was 42.2 (30-70) y in Group I and 42.13 (28-61) y in Group II. The maximal glandular circumference was significantly increased compared to basal circumference of 9.13+/-0.64 cm in Group I (P<0.01) and 9.49+/-1.05 cm in Group II (P<0.01) at 1 y after injection. Net increase of maximal glandular circumference after glans augmentation was 14.93+/-0.80 mm in Group I and 14.78+/-0.89 mm in Group II. In patient's visual estimation, more than 50% of injected volume was maintained in 95% of Group 1 and 100% of Group II. The percentage of postoperative satisfaction (Gr 4, 5) was 77% in Group 1 and 69% in Group II. There was no abnormal reaction in area feeling, texture, and color. In most cases, initial discoloration by glandular swelling recovered to normal within 2 weeks. There were no signs of inflammation and no serious adverse reactions in all cases. These results suggest that injectable hyaluronic acid gel is a safe and effective material for augmentation of glans penis.
Indexed as
Identifiers
14671664What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.