ArticlePediatric nephrology (Berlin, Germany)2004
Ultrasonography in the evaluation of renal scarring using DMSA scan as the gold standard.
Article in Pediatric nephrology (Berlin, Germany), 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 73 citations in OpenAlex.
- Upper and lower urinary tract outcomes in adult myelomeningocele patients: a systematic review.PloS one · 2012Pooled it
- Comparative analysis of renal parenchymal thickness and hydronephrosis: A technetium-99m dimercaptosuccinic acid single-photon emission CT and ultrasonography study.Asian journal of urology · 2026Article
- Renal Cortical Imaging with Tc-99m DMSA in Children: An Institutional Review.World journal of nuclear medicine · 2024Article
- What are the Optimal Renal Ultrasound Parameters for Detecting Small Kidney in Young Children?Research and reports in urology · 2021Article
- In children with urinary tract infection reduced kidney length and vesicoureteric reflux predict abnormal DMSA scan.Pediatric research · 2020Article
- Vesicoureteral Reflux and Renal Scarring in Infants After the First Febrile Urinary Tract Infection.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2018Article
- Dimercaptosuccinic acid scintigraphy vs. ultrasound for renal parenchymal defects in children.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2017Article
- Decreased Identification of Vesicoureteral Reflux: A Cautionary Tale.Frontiers in pediatrics · 2017Article
- Prediction of primary vs secondary hypertension in children.Journal of clinical hypertension (Greenwich, Conn.) · 2012Article
- Primary, nonsyndromic vesicoureteric reflux and nephropathy in sibling pairs: a United Kingdom cohort for a DNA bank.Clinical journal of the American Society of Nephrology : CJASN · 2011Article
- Evaluation of dynamic contrast-enhanced MRI in detecting renal scarring in a rat injury model.Journal of magnetic resonance imaging : JMRI · 2010Article
- Sensitivity of ultrasonography in detecting renal parenchymal defects: 6 years' follow-up.Pediatric nephrology (Berlin, Germany) · 2009Article
- Value of comprehensive renal ultrasound in children with acute urinary tract infection for assessment of renal involvement: comparison with DMSA scintigraphy and final diagnosis.European radiology · 2008Article
- Urinary tract infections in children.Current urology reports · 2008Review
- Dimercaptosuccinic acid (DMSA) renal scan in the evaluation of hypertension in children.Pediatric nephrology (Berlin, Germany) · 2008Article
- Imaging strategies for vesicoureteral reflux diagnosis.Pediatric nephrology (Berlin, Germany) · 2007Article
- Applying the ALARA concept to the evaluation of vesicoureteric reflux.Pediatric radiology · 2006Review
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dimercaptosuccinic acid (DMSA) renal scan is presently the technique of choice for assessing renal scars. Recent advances suggest that ultrasonography could replace DMSA scan for this purpose. This paper describes the experience of a tertiary pediatric referral hospital performing ultrasonography and DMSA scans in the assessment of renal scarring. Investigations were conducted 3-6 months after patients presented with urinary tract infection (UTI). Results were extracted from the radiology information system and recorded for analysis. All children with a UTI who had undergone DMSA and ultrasound examination on the same day between January 1995 and December 1999 were included; 930 kidneys were compared. DMSA scan was utilized as the reference method. When used to detect focal renal scarring, ultrasonography had a sensitivity of 5.2%, specificity of 98.3%, a positive predictive value (PPV) of 50% and a negative predictive value (NPV) of 75.8%. When used to detect diffuse renal scarring, ultrasonography had a sensitivity of 47.2%, specificity of 91.8%, PPV of 60.8% and NPV of 86.6%. Our results demonstrate that although ultrasonography has a good specificity for the detection of renal scarring compared with DMSA, it has low sensitivity, PPV and NPV. Ultrasonography cannot be substituted for DMSA scan in the evaluation of focal renal scarring.
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