ArticleProceedings of the National Academy of Sciences of the United States of America1992
The PR264/c-myb connection: expression of a splicing factor modulated by a nuclear protooncogene.
Article in Proceedings of the National Academy of Sciences of the United States of America, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Alteration of C-MYB DNA binding to cognate responsive elements in HL-60 variant cells.Molecular pathology : MP · 2002Article
- Evidence for the function of an exonic splicing enhancer after the first catalytic step of pre-mRNA splicing.Proceedings of the National Academy of Sciences of the United States of America · 1999Article
- Differential gene expression in neoplastic and human papillomavirus-immortalized oral keratinocytes.Oncogene · 1999Article
- Characterization of SRp46, a novel human SR splicing factor encoded by a PR264/SC35 retropseudogene.Molecular and cellular biology · 1998Article
- Overexpression of A-myb induces basic fibroblast growth factor-dependent proliferation of chicken neuroretina cells.Journal of virology · 1997Article
- Characterization of multiple alternative RNAs resulting from antisense transcription of the PR264/SC35 splicing factor gene.Nucleic acids research · 1997Article
- Retroviral insertional activation of the c-myb proto-oncogene in a Marek's disease T-lymphoma cell line.Journal of virology · 1996Article
- Binding site analysis of c-Myb: screening of potential binding sites by using the mutation matrix derived from systematic binding affinity measurements.Nucleic acids research · 1996Article
- Casein kinase II phosphorylation site mutations in c-Myb affect DNA binding and transcriptional cooperativity with NF-M.Molecular and cellular biology · 1995Article
- The BCMA gene, preferentially expressed during B lymphoid maturation, is bidirectionally transcribed.Nucleic acids research · 1994Article
- Several mRNAs with variable 3' untranslated regions and different stability encode the human PR264/SC35 splicing factor.Proceedings of the National Academy of Sciences of the United States of America · 1994Article
- DNA and redox state induced conformational changes in the DNA-binding domain of the Myb oncoprotein.The EMBO journal · 1993Article
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Authors and funding
5 authors.
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Abstract
We have previously reported that expression of the c-myb gene in normal avian thymic cells proceeds through the intermolecular recombination of ET (thymus-specific) and c-myb coding sequences, thereby generating a novel type of c-myb product. Antisense transcripts expressed from the ET locus encode the extremely well-conserved splicing factor PR264/SC35. We now show that the human PR264 promoter sequences contain several myb-recognition elements that efficiently interact in vitro with the c-myb DNA-binding domain. Moreover, expression from the PR264 promoter is transactivated, both in vitro and in cultured cells, by different c-myb products. Thus, the PR264 gene is most likely a physiological target for the c-myb family of transcription factors.
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