Evidence map›Paper›PMID 14648244›Full record

Trial reportHernia : the journal of hernias and abdominal wall surgery2004

Early results of a single-blinded, randomized, controlled, Internet-based multicenter trial comparing Prolene and Vypro II mesh in Lichtenstein hernioplasty.

Sven Bringman, Timo-Jaakko Heikkinen, Staffan Wollert, Johanna Osterberg, Sam Smedberg, Håkan Granlund, Stig Ramel, Göran Felländer, Bo Anderberg

Abstract readClinical TrialComparative StudyMulticenter Study
PubMed Publisher
In one paragraph

Trial report in Hernia : the journal of hernias and abdominal wall surgery, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Lightweight versus heavyweight in inguinal hernia repair: a meta-analysis.Hernia : the journal of hernias and abdominal wall surgery · 2012
    Pooled it
  4. European Hernia Society guidelines on the treatment of inguinal hernia in adult patients.Hernia : the journal of hernias and abdominal wall surgery · 2009
    Guideline
  5. Trial
  6. Trial
  7. Trial
  8. Trial
  9. Trial
  10. Trial
  11. Review
  12. Varying convalescence recommendations after inguinal hernia repair: a systematic scoping review.Hernia : the journal of hernias and abdominal wall surgery · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Tension-free open hernia repair using an innovative self-gripping semi-resorbable mesh.Hernia : the journal of hernias and abdominal wall surgery · 2009
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sven BringmanCenter For Surgical Sciences, K53 Karolinska Institutet at Huddinge University Hospital, 141 86, Stockholm, Sweden. sven.bringman@cfss.ki.se
Timo-Jaakko Heikkinen
Staffan Wollert
Johanna Osterberg
Sam Smedberg
Håkan Granlund
Stig Ramel
Göran Felländer
Bo Anderberg

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe standard polypropylene mesh used in Lichtenstein's operation induces a strong foreign-tissue reaction with potentially harmful effects. A mesh with less polypropylene could possibly be beneficial. PATIENTS AND

methodsSix hundred men with inguinal hernias were randomized to Lichtenstein's operation with Prolene or Vypro II in a single-blinded multicenter trial. The randomization was performed by a computer algorithm in a database through the Internet. All data were entered and directly validated in the database through the Internet.

resultsThe meshes had comparable results in return to work, return to daily activities, complications, postoperative pain, and quality of life during the first 8 weeks of rehabilitation.

conclusionsLichtenstein's operation with either Prolene or Vypro II is safe and well tolerated with an acceptable postoperative rehabilitation time and a high quality of life 2 months after surgery. The study was facilitated by the use of a database through the Internet.

Indexed as

Polyglactin 910PolypropylenesSurgical MeshAdultAgedHernia, InguinalHumansInternetMaleMiddle AgedPostoperative ComplicationsQuality of LifeRandomized Controlled Trials as TopicSingle-Blind MethodPolyglactin 910Polypropylenes

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.