ArticleDevelopment genes and evolution2004
Embryonic origins of the two main classes of hemocytes--granular cells and plasmatocytes--in Manduca sexta.
Article in Development genes and evolution, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 41 citations in OpenAlex.
- Hematopoietic plasticity mapped ineLife · 2022Review
- Where you come from matters: temperature influences host-parasitoid interaction through parental effects.Oecologia · 2020Article
- Insect immunology and hematopoiesis.Developmental and comparative immunology · 2016Review
- Eicosanoids mediate Galleria mellonella immune response to hemocoel injection of entomopathogenic nematode cuticles.Parasitology research · 2016Article
- Self-assembled insect muscle bioactuators with long term function under a range of environmental conditions.RSC advances · 2014Article
- Host plant quality, selection history and trade-offs shape the immune responses of Manduca sexta.Proceedings. Biological sciences · 2011Article
- Article
- Immunity in lepidopteran insects.Advances in experimental medicine and biology · 2010Review
- Localisation of laminin within Plasmodium berghei oocysts and the midgut epithelial cells of Anopheles stephensi.Parasites & vectors · 2008Article
- Subdivision and developmental fate of the head mesoderm in Drosophila melanogaster.Development genes and evolution · 2006Article
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Authors and funding
1 author at 1 institution in 1 country.
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Abstract
Cell-mediated responses of the moth immune system involve the interaction of two main classes of hemocytes-granular cells and plasmatocytes. During embryogenesis, granular cells arise much earlier than plasmatocytes, and the presence of granular cells is closely coupled with the formation of basal laminae that line the hemocoel occupied by hemocytes. Although epithelial cells contribute the large extracellular matrix protein lacunin to embryonic matrices before granular cells begin contributing this protein to basal laminae, the spatial pattern of lacunin expression in early embryos parallels the later distribution of granular cells over surfaces of basal laminae. Plasmatocytes arise late in embryogenesis, after the cessation of the major morphogenetic movements and the establishment of intact basal laminae. Granular cells are intimately involved with remodeling of basal laminae, and disruptions in the structure of basal laminae can trigger an autoimmune response of granular cells and plasmatocytes. By arising after basal laminae have been molded and remodeled by granular cells, plasmatocytes presumably do not encounter the cues that trigger their aggregation and an autoimmune response.
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