ArticleBritish journal of cancer2003
Risk factors for adenocarcinoma and squamous cell carcinoma of the cervix in women aged 20-44 years: the UK National Case-Control Study of Cervical Cancer.
Article in British journal of cancer, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 2 of them syntheses that pooled it.
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Who cites it
37 citing papers in PubMed, 2 syntheses or guidelines pooled it, 155 citations in OpenAlex.
- Comparison of risk factors for squamous cell and adenocarcinomas of the cervix: a meta-analysis.British journal of cancer · 2004Pooled it
- High parity is associated with increased risk of cervical cancer: Systematic review and meta-analysis of case-control studies.Women's health (London, England)Pooled it
- Prevalence of Cervical Pap Smear Epithelial Abnormalities in Iraqi Women and Its Correlation with Histopathology.Iranian journal of pathology · 2026Article
- Association Between Metabolic Syndrome and Incident Cervical Cancer: A Retrospective Cohort Study.Journal of obesity · 2025Article
- Article
- Initial treatment for FIGO 2018 stage IIIC cervical cancer based on histological type: A 14-year multicenter study.Cancer medicine · 2023Article
- Circulating HPV DNA as a Biomarker for Pre-Invasive and Early Invasive Cervical Cancer: A Feasibility Study.Cancers · 2023Article
- HPV and Cervical Cancer: A Review of Epidemiology and Screening Uptake in the UK.Pathogens (Basel, Switzerland) · 2023Review
- Early-onset of sexual activity as a potential risk of cervical cancer in Africa: A review of literature.PLOS global public health · 2023Article
- Knowledge and Attitude Regarding Cervical Cancer and Human Papillomavirus in Oman.Sultan Qaboos University medical journal · 2022Article
- Tumor histology is an independent prognostic factor in locally advanced cervical carcinoma: A retrospective study.BMC cancer · 2022Observational
- Prevalence of Cytological Abnormalities in Papanicolaou Smears and Risk Factors for Cervical Cancer Among Women in Muscat, Oman.Sultan Qaboos University medical journal · 2021Article
- Risk factors of cervical cancer after a negative cytological diagnosis in Polish cervical cancer screening programme.Cancer medicine · 2021Article
- Comparing survival outcomes for cervical cancer based on the 2014 and 2018 International Federation of Gynecology and Obstetrics staging systems.Scientific reports · 2021Article
- Contraception in chronic kidney disease: a best practice position statement by the Kidney and Pregnancy Group of the Italian Society of Nephrology.Journal of nephrology · 2020Article
- Hyperchromatic-crowded groups (HCG) in pap smears.CytoJournal · 2020Article
- A Review of Computational Methods for Cervical Cells Segmentation and Abnormality Classification.International journal of molecular sciences · 2019Review
- Different expression of GSK3β and pS9GSK3β depending on phenotype of cervical cancer: possible association of GSK3β with squamous cell carcinoma and pS9GSK3β with adenocarcinoma.Obstetrics & gynecology science · 2019Article
- Impact of tumour histology on survival in advanced cervical carcinoma: an NRG Oncology/Gynaecologic Oncology Group Study.British journal of cancer · 2018Article
- SOX2 as a New Regulator of HPV16 Transcription.Viruses · 2017Article
Corrections and comments
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Authors and funding
13 authors at 6 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We report results on risk factors for invasive squamous cell and adenocarcinomas of the cervix in women aged 20-44 years from the UK National Case-Control Study of Cervical Cancer, including 180 women with adenocarcinoma, 391 women with squamous cell carcinoma and 923 population controls. The risk of both squamous cell and adenocarcinoma was strongly related to the lifetime number of sexual partners, and, independently, to age at first intercourse. The risk of both types of cervical cancer increased with increasing duration of use of oral contraceptives, and this effect was most marked in current and recent users of oral contraceptives. The risk of squamous cell carcinoma was associated with high parity and the risk of both squamous cell and adenocarcinoma increased with early age at first birth. Long duration smoking (20 or more years) was associated with a two-fold increase in the risk of squamous cell carcinoma, but smoking was not associated with the risk of adenocarcinoma. Further studies are needed to confirm the suggestion from this and other studies of differences in risk related to smoking between squamous cell and adenocarcinomas of the cervix.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.