Trial reportThorax2003
Association of body mass with pulmonary function in the Childhood Asthma Management Program (CAMP).
Trial report in Thorax, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00000575 (Childhood Asthma Management Program), which is not on this map. Cited by 103 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Childhood Asthma Management Program
Who cites it
103 citing papers in PubMed, 3 syntheses or guidelines pooled it, 247 citations in OpenAlex.
- Comparative response to pharmacological management of asthma in overweight/obese childrenEuropean respiratory review : an official journal of the European Respiratory Society · 2026Pooled it
- Nedocromil sodium for chronic asthma in children.The Cochrane database of systematic reviews · 2006Pooled it
- Overweight, Obesity, and Lung Function in Children and Adults-A Meta-analysis.The journal of allergy and clinical immunology. In practicePooled it
- Trial
- Obesity and adiposity indicators, asthma, and atopy in Puerto Rican children.The Journal of allergy and clinical immunology · 2014Trial
- Obesity in children with poorly controlled asthma: Sex differences.Pediatric pulmonology · 2013Trial
- Associations of postnatal growth with asthma and atopy: the PROBIT Study.Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology · 2013Trial
- Airway responsiveness in mild to moderate childhood asthma: sex influences on the natural history.American journal of respiratory and critical care medicine · 2008Trial
- Airway Obstruction Worsens in Young Adults with Asthma Who Become Obese.The journal of allergy and clinical immunology. In practiceTrial
- Circulating microRNAs Predict Longitudinal Asthma Control and Treatment Response.medRxiv : the preprint server for health sciences · 2026Article
- Assessment of ventilation distribution in overweight and obese children with asthma using electric impedance tomography: a cross-sectional study.Italian journal of pediatrics · 2026Article
- Sex, hormones, and lung health.Physiological reviews · 2026Review
- Effects of metabolic syndrome on pulmonary infection in pediatric bronchial asthma: a narrative review.Frontiers in pediatrics · 2026Review
- Evaluation of bronchial hyperresponsiveness in asthmatic paediatric patients using mannitol challenge test - Impacts of body mass index.Annals of medicine · 2025Article
- Association between the Body Roundness Index and spirometric parameters among U.S. Adolescents from NHANES 2007-2012.BMC pulmonary medicine · 2025Article
- Effect of metabolic syndrome on pulmonary dysfunction in children with asthma.Clinical and experimental pediatrics · 2025Article
- Exercise-induced bronchoconstriction in children: Delphi study and consensus document about definition and epidemiology, diagnostic work-up, treatment, and follow-up.Respiratory research · 2024Article
- A clinician's guide to effects of obesity on childhood asthma and into adulthood.Expert review of respiratory medicine · 2024Review
- Relationship between obesity, body composition, and pulmonary function among Korean adults aged 40 years and older.Scientific reports · 2024Article
- Exercise-Induced Bronchoconstriction in Children: State of the Art from Diagnosis to Treatment.Journal of clinical medicine · 2024Review
43 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
backgroundWhile increases in body mass index (BMI) have been associated with the incidence and prevalence of asthma, the mechanisms behind this association are unclear.
methodsWe hypothesised that BMI would be independently associated with measures of asthma severity in a population of children with mild to moderate asthma enrolled in the Childhood Asthma Management Program (CAMP). A multivariable baseline cross sectional analysis of BMI with our outcomes of interest was performed.
resultsBMI was generally not associated with symptoms, nor was it associated with atopy. While BMI was positively associated with the methacholine concentration that causes a 20% fall in forced expiratory volume in 1 second (PC(20)FEV(1)), this association did not persist after adjustment for FEV(1). Increasing BMI was associated with increasing FEV(1) (beta = 0.006 l, 95% CI (0.001 to 0.01)) and forced vital capacity (FVC) (beta = 0.012 l, 95% CI (0.007 to 0.017)). However, decrements in the FEV(1)/FVC ratio were noted with increasing BMI (beta = -0.242, 95% CI (-0.118 to -0.366)). Thus, an increase in BMI of 5 units was associated with a decrease in FEV(1)/FVC of over 1%.
conclusionsAlthough the association of FEV(1) and FVC with BMI did not support our initial hypothesis, the decrease noted in the FEV(1)/FVC ratio has potential relevance in the relationship between BMI and asthma severity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.