Evidence map›Paper›PMID 14641933›Full record

ArticleBMC infectious diseases2003

vCJD risk in the Republic of Ireland.

Michael S Harney, Azra C Ghani, C A Donnelly, Rory McConn Walsh, Michael Walsh, Rachel Howley, Francesca Brett, Michael Farrell

Abstract read
In one paragraph

Article in BMC infectious diseases, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Michael S HarneyCJD Surveillance Unit, Beaumont Hospital, Dublin, Ireland. michaelsharney@eircom.net
Azra C Ghani
C A Donnelly
Rory McConn Walsh
Michael Walsh
Rachel Howley
Francesca Brett
Michael Farrell

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Republic of Ireland has the second highest incidence of BSE worldwide. Only a single case of vCJD has been identified to date.

methodsWe estimate the total future number of clinical cases of vCJD using an established mathematical model, and based on infectivity of bovine tissue calculated from UK data and on the relative exposure to BSE contaminated meat.

resultsWe estimate 1 future clinical case (95% CI 0-15) of vCJD in the Republic of Ireland. Irish exposure is from BSE infected indigenous beef products and from imported UK beef products. Additionally, 2.5% of the Irish population was exposed to UK beef through residing in the UK during the 'at-risk' period. The relative proportion of risk attributable to each of these three exposures individually is 2:2:1 respectively.

conclusionsThe low numbers of future vCJD cases estimated in this study is reassuring for the Irish population and for other countries with a similar level of BSE exposure.

Indexed as

Models, BiologicalAnimalsCattleCreutzfeldt-Jakob SyndromeEncephalopathy, Bovine SpongiformFood ContaminationHumansIncidenceIrelandMeat ProductsRisk Factors

Identifiers

PMID14641933
PMCPMC305349

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.