ArticleClinical cardiology2003
Insulin resistance and maximal oxygen uptake.
Article in Clinical cardiology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.
- Exercise and diabetes-related cardiovascular disease: systematic review of published evidence from observational studies and clinical trials.Current diabetes reports · 2013Pooled it
- Research into the effect Of SGLT2 inhibition on left ventricular remodelling in patients with heart failure and diabetes mellitus (REFORM) trial rationale and design.Cardiovascular diabetology · 2016Trial
- Cardiovascular phenotype in HFpEF patients with or without diabetes: a RELAX trial ancillary study.Journal of the American College of Cardiology · 2014Trial
- Comparing the Metabolic Profiles Associated with Fitness Status between Insulin-Sensitive and Insulin-Resistant Non-Obese Individuals.International journal of environmental research and public health · 2022Article
- Inflammatory, antioxidant and glycemic status to different mode of high-intensity training in type 2 diabetes mellitus.Molecular biology reports · 2021Article
- Association between aerobic capacity and the improvement in glycemic control after the exercise training in type 2 diabetes.Diabetology & metabolic syndrome · 2017Article
- Insulin levels and HOMA index are associated with exercise capacity in patients with type 2 diabetes and coronary artery disease.Diabetology & metabolic syndrome · 2014Article
- Anti-aging therapy through fitness enhancement.Clinical interventions in aging · 2006Review
- Type 2 diabetes mellitus and cardiovascular exercise performance.Reviews in endocrine & metabolic disorders · 2004 · on this mapReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundType 2 diabetes, coronary atherosclerosis, and physical fitness all correlate with insulin resistance, but the relative importance of each component is unknown. HYPOTHESIS: This study was undertaken to determine the relationship between insulin resistance, maximal oxygen uptake, and the presence of either diabetes or ischemic heart disease.
methodsThe study population comprised 33 patients with and without diabetes and ischemic heart disease. Insulin resistance was measured by a hyperinsulinemic euglycemic clamp; maximal oxygen uptake was measured during a bicycle exercise test.
resultsThere was a strong correlation between maximal oxygen uptake and insulin-stimulated glucose uptake (r = 0.7, p = 0.001), and maximal oxygen uptake was the only factor of importance for determining insulin sensitivity in a model, which also included the presence of diabetes and ischemic heart disease.
conclusionMaximal oxygen uptake may be a more important determinant for insulin sensitivity than ischemic heart disease and type 2 diabetes.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.