ArticleJournal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology2004
Physiological and morphological characterization of honeybee olfactory neurons combining electrophysiology, calcium imaging and confocal microscopy.
Article in Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology, 2004. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers.
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Who cites it
43 citing papers in PubMed.
- Antennal Lobe Dynamics And The Generation Of Diverse Response Patterns To Mechanosensory Stimulation.bioRxiv : the preprint server for biology · 2026Article
- Multi-unit recordings in the stick insectFrontiers in physiology · 2026Article
- Article
- In Vivo Two-Photon Imaging of the Olfactory System in Insects.Methods in molecular biology (Clifton, N.J.) · 2025Article
- Heterogeneous receptor expression underlies non-uniform peptidergic modulation of olfaction in Drosophila.Nature communications · 2023Article
- Gain modulation and odor concentration invariance in early olfactory networks.PLoS computational biology · 2023Article
- Article
- Learning-dependent plasticity in the antennal lobe improves discrimination and recognition of odors in the honeybee.Cell and tissue research · 2021Review
- Olfactory coding in honeybees.Cell and tissue research · 2021Review
- Experience-dependent tuning of early olfactory processing in the adult honey bee,The Journal of experimental biology · 2020Article
- Neuronal Response Latencies Encode First Odor Identity Information across Subjects.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
- An Early Sensitive Period Induces Long-Lasting Plasticity in the Honeybee Nervous System.Frontiers in behavioral neuroscience · 2018Article
- DNA methylation mediates neural processing after odor learning in the honeybee.Scientific reports · 2017Article
- Learning about natural variation of odor mixtures enhances categorization in early olfactory processing.The Journal of experimental biology · 2016Article
- Article
- Space Takes Time: Concentration Dependent Output Codes from Primary Olfactory Networks Rapidly Provide Additional Information at Defined Discrimination Thresholds.Frontiers in cellular neuroscience · 2015Article
- Oral dosing of chemical indicators for in vivo monitoring of Ca2+ dynamics in insect muscle.PloS one · 2015Article
- Rapid and slow chemical synaptic interactions of cholinergic projection neurons and GABAergic local interneurons in the insect antennal lobe.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Article
- Simultaneous long-term recordings at two neuronal processing stages in behaving honeybees.Journal of visualized experiments : JoVE · 2014Article
- Olfactory coding in the insect brain: data and conjectures.The European journal of neuroscience · 2014Review
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Authors and funding
2 authors.
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No grant is acknowledged in the PubMed record.
Abstract
The insect antennal lobe is the first brain structure to process olfactory information. Like the vertebrate olfactory bulb the antennal lobe is substructured in olfactory glomeruli. In insects, glomeruli can be morphologically identified, and have characteristic olfactory response profiles. Local neurons interconnect glomeruli, and output (projection) neurons project to higher-order brain centres. The relationship between their elaborate morphology and their physiology is not understood. We recorded electrophysiologically from antennal lobe neurons, and iontophoretically injected a calcium-sensitive dye. We then measured their spatio-temporal calcium responses to a variety of odours. Finally, we confocally reconstructed the neurons, and identified the innervated glomeruli. An increase or decrease in spiking frequency corresponded to an intracellular calcium increase or decrease in the cell. While intracellular recordings generally lasted between 10 and 30 min, calcium imaging was stable for up to 2 h, allowing a more detailed physiological analysis. The responses indicate that heterogeneous local neurons get input in the glomerulus in which they branch most strongly. In many cases, the physiological response properties of the cells corresponded to the known response profile of the innervated glomerulus. In other words, the large variety of response profiles generally found when comparing antennal lobe neurons is reduced to a more predictable response profile when the innervated glomerulus is known.
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