Evidence map›Paper›PMID 14638823›Full record

ArticleInfection and immunity2003

Enhanced phagocytosis of Candida species mediated by opsonization with a recombinant human antibody single-chain variable fragment.

Melanie Wellington, Joseph M Bliss, Constantine G Haidaris

Open access · greenAbstract read
In one paragraph

Article in Infection and immunity, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Melanie WellingtonDepartment of Pediatrics, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA.
Joseph M Bliss
Constantine G Haidaris
University of Rochester · US

Funding

TRAINING IN PEDIATRIC INFECTIOUS DISEASEST32AI007464 · NIAID · UNIVERSITY OF ROCHESTER · PI GIGLIOTTI, FRANCIS · 1995 to 2014
$2.2M
NIAID NIH HHS T32 AI007464NIAID NIH HHS T32 AI07464
6 · The paper itself

Abstract

Specific antibody opsonization significantly enhances the level of phagocytosis of Candida in the absence of complement. Furthermore, we have described a system using a recombinant human antibody single-chain variable fragment that allows a comparative study of phagocytosis of multiple Candida species opsonized via a common antigen.

Indexed as

PhagocytosisAntibodies, FungalCandidaHumansImmunoglobulin FragmentsImmunoglobulin Variable RegionMonocytesNeutrophilsOpsonin ProteinsRecombinant ProteinsAntibodies, FungalImmunoglobulin FragmentsImmunoglobulin Variable RegionOpsonin ProteinsRecombinant Proteins

Identifiers

PMID14638823
PMCPMC308946
OpenAlexW2118992062

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.