Evidence map›Paper›PMID 14638822›Full record

ArticleInfection and immunity2003

Mycobacterium avium subsp. paratuberculosis infection causes suppression of RANTES, monocyte chemoattractant protein 1, and tumor necrosis factor alpha expression in peripheral blood of experimentally infected cattle.

Joram J Buza, Yasuyuki Mori, Abusaleh M Bari, Hirokazu Hikono, Aodon-geril, Sachiyo Hirayama, Yujing Shu, Eiichi Momotani

Open access · greenAbstract read
In one paragraph

Article in Infection and immunity, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 31 citations in OpenAlex.

  1. Single-nucleotide polymorphisms inJournal of genetics · 2020
    Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Poor maternal nutrition inhibits muscle development in ovine offspring.Journal of animal science and biotechnology · 2014
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Joram J BuzaParatuberculosis and Inflammatory Bowel Disease Research Team, National Institute of Animal Health, 3-1-5 Kan-nondai, Tsukuba 305-0856, Japan.
Yasuyuki Mori
Abusaleh M Bari
Hirokazu Hikono
Aodon-geril
Sachiyo Hirayama
Yujing Shu
Eiichi Momotani
National Institute of Animal Health · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Blood from cattle with subclinical Mycobacterium avium subsp. paratuberculosis infection was stimulated with M. avium subsp. paratuberculosis antigens, and expression of interleukin-1beta (IL-1beta), tumor necrosis factor alpha (TNF-alpha), RANTES, monocyte chemoattractant protein 1 (MCP-1), and IL-8 was measured. Expression of TNF-alpha, RANTES, and MCP-1 was lower in infected than in uninfected cattle. The reduced response may weaken protective immunity and perpetuate infection.

Indexed as

AnimalsCattleCattle DiseasesChemokine CCL2Chemokine CCL5Mycobacterium avium subsp. paratuberculosisParatuberculosisTumor Necrosis Factor-alphaChemokine CCL2Chemokine CCL5Tumor Necrosis Factor-alpha

Identifiers

PMID14638822
PMCPMC308884
OpenAlexW2147072532

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.