Evidence map›Paper›PMID 14638815›Full record

ArticleInfection and immunity2003

The activation of bovine plasminogen by PauA is not required for virulence of Streptococcus uberis.

Philip N Ward, Terence R Field, Christopher D Rapier, James A Leigh

Abstract read
In one paragraph

Article in Infection and immunity, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Evaluation ofVaccines · 2021
    Article
  2. EnvironmentalAnimals : an open access journal from MDPI · 2021
    Article
  3. Genotyping and Antimicrobial Susceptibility Profiling ofAntibiotics (Basel, Switzerland) · 2021
    Article
  4. Article
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Philip N WardInstitute for Animal Health, Compton Laboratory, Compton, Newbury, Berks, United Kingdom RG20 7NN.
Terence R Field
Christopher D Rapier
James A Leigh

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A mutant of Streptococcus uberis carrying a single copy of ISS1 within pauA was unable to activate bovine plasminogen. Contrary to a hypothesis postulated previously, this mutation did not alter the ability of the bacterium to grow in milk or to infect the lactating bovine mammary gland.

Indexed as

AnimalsBacterial ProteinsCattleCattle DiseasesFemaleLactationMammary Glands, AnimalMastitis, BovinePlasminogenPlasminogen ActivatorsStreptococcusVirulenceBacterial ProteinsPauA protein, Streptococcus uberisPlasminogenPlasminogen Activators

Identifiers

PMID14638815
PMCPMC308948

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.