ArticleAntimicrobial agents and chemotherapy2003
Acquired macrolide resistance genes in pathogenic Neisseria spp. isolated between 1940 and 1987.
Article in Antimicrobial agents and chemotherapy, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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Who cites it
20 citing papers in PubMed.
- The Synergistic Armory: A Global Genome-Wide Association Study Reveals the Integrated Mechanisms of Azithromycin Resistance inInternational journal of molecular sciences · 2026Article
- Rolling the evolutionary dice:Microbiology spectrum · 2024Article
- Emerging threat of antimicrobial resistance in Neisseria gonorrhoeae: pathogenesis, treatment challenges, and potential for vaccine development.Archives of microbiology · 2023Review
- Emergence of Azithromycin-ResistantMicroorganisms · 2023Article
- Azithromycin Susceptibility Testing and Molecular Investigation ofAntibiotics (Basel, Switzerland) · 2023Article
- Molecular Mechanisms of Drug Resistance and Epidemiology of Multidrug-Resistant Variants ofInternational journal of molecular sciences · 2022Review
- A community-driven resource for genomic epidemiology and antimicrobial resistance prediction of Neisseria gonorrhoeae at Pathogenwatch.Genome medicine · 2021Article
- Multiresistant Neisseria gonorrhoeae: a new threat in second decade of the XXI century.Medical microbiology and immunology · 2020Review
- Rapid molecular detection of macrolide resistance.BMC infectious diseases · 2019Article
- Genomic epidemiology and antimicrobial resistance of Neisseria gonorrhoeae in New Zealand.The Journal of antimicrobial chemotherapy · 2018Article
- Mechanisms of Bacterial Resistance to Antimicrobial Agents.Microbiology spectrum · 2018Article
- Molecular analysis of antimicrobial resistance mechanisms in Neisseria gonorrhoeae isolates from Ontario, Canada.Antimicrobial agents and chemotherapy · 2011Article
- Determination of CEM-101 activity tested against clinical isolates of Neisseria meningitidis from a worldwide collection.Antimicrobial agents and chemotherapy · 2010Article
- The impact of the neisserial DNA uptake sequences on genome evolution and stability.Genome biology · 2008Article
- Molecular characterization of pneumococci with efflux-mediated erythromycin resistance and identification of a novel mef gene subclass, mef(I).Antimicrobial agents and chemotherapy · 2005Article
- Molecular detection of the macrolide efflux gene: to discriminate or not to discriminate between mef(A) and mef(E).Antimicrobial agents and chemotherapy · 2005Review
- Resistance to macrolide, lincosamide, streptogramin, ketolide, and oxazolidinone antibiotics.Molecular biotechnology · 2004Review
- The mef(A) gene predominates among seven macrolide resistance genes identified in gram-negative strains representing 13 genera, isolated from healthy Portuguese children.Antimicrobial agents and chemotherapy · 2004Article
- Gonorrhea Update.Current infectious disease reports · 2004Article
- Whole-Genome Sequencing of Russian Neisseria Gonorrhoeae Isolates Related to ST 1407 Genogroup.Acta naturaeArticle
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3 authors.
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Abstract
Seventy-six Neisseria gonorrhoeae isolates, isolated between 1940 and 1987, and seven Neisseria meningitidis isolates, isolated between 1963 and 1987, were screened for the presence of acquired mef(A), erm(B), erm(C), and erm(F) genes by using DNA-DNA hybridization, PCR analysis, and sequencing. The mef(A), erm(B), and erm(F) genes were all identified in a 1955 N. gonorrhoeae isolate, while the erm(C) gene was identified in a 1963 N. gonorrhoeae isolate. Similarly, both the mef(A) and erm(F) genes were identified in a 1963 N. meningitidis isolate. All four acquired genes were found in later isolates of both species. The mef(A) gene from a 1975 N. gonorrhoeae isolate was sequenced and had 100% DNA and amino acid identity with the mef(A) gene from a 1990s Streptococcus pneumoniae isolate. Selected early isolates were able to transfer their acquired genes to an Enterococcus faecalis recipient, suggesting that these genes are associated with conjugative transposons. These isolates are the oldest of any species to carry the mef(A) gene and among the oldest to carry these erm genes.
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