ReviewJournal of bioenergetics and biomembranes2003
A journey from mammals to yeast with vacuolar H+-ATPase (V-ATPase).
Review in Journal of bioenergetics and biomembranes, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
31 citing papers in PubMed, 79 citations in OpenAlex.
- Synthesis of Diphenyl Sulfonamide Derivatives as Potential Inhibitors of V-ATPase.Current organic synthesis · 2026Article
- Investigation of Isoform Specific Functions of the V-ATPase a Subunit DuringFrontiers in genetics · 2020Article
- Atg1-mediated autophagy suppresses tissue degeneration inMolecular biology of the cell · 2018Article
- Direct interaction of the Golgi V-ATPase a-subunit isoform with PI(4)P drives localization of Golgi V-ATPases in yeast.Molecular biology of the cell · 2017Article
- Regulation of Vacuolar H+-ATPase (V-ATPase) Reassembly by Glycolysis Flow in 6-Phosphofructo-1-kinase (PFK-1)-deficient Yeast Cells.The Journal of biological chemistry · 2016Article
- Separation of Binding Protein of Celangulin V from the Midgut of Mythimna separata Walker by Affinity Chromatography.Toxins · 2015Article
- Cloning, expression and purification of subunit H of vacuolar H⁺-ATPase from Mythimna separata Walker (Lepidoptera: Noctuidae).International journal of molecular sciences · 2014Article
- Suppressing dengue-2 infection by chemical inhibition of Aedes aegypti host factors.PLoS neglected tropical diseases · 2014Article
- Interaction of the tick immune system with transmitted pathogens.Frontiers in cellular and infection microbiology · 2013Review
- Japanese encephalitis virus enters rat neuroblastoma cells via a pH-dependent, dynamin and caveola-mediated endocytosis pathway.Journal of virology · 2012Article
- Proteomic study of the mucin granulae in an intestinal goblet cell model.Journal of proteome research · 2012Article
- Differential salivary gland transcript expression profile in Ixodes scapularis nymphs upon feeding or flavivirus infection.Ticks and tick-borne diseases · 2012Article
- Bundling actin filaments from membranes: some novel players.Frontiers in plant science · 2012Article
- Intracellular trafficking in Drosophila visual system development: a basis for pattern formation through simple mechanisms.Developmental neurobiology · 2011Review
- Role of the vacuolar-ATPase in Sindbis virus infection.Journal of virology · 2011Article
- Regulation and isoform function of the V-ATPases.Biochemistry · 2010Review
- The vacuolar proton pump, V-ATPase, is required for notch signaling and endosomal trafficking in Drosophila.Developmental cell · 2009Article
- Vacuolar H(+)-ATPase-an enzyme for all seasons.Pflugers Archiv : European journal of physiology · 2009Review
- Function, structure and regulation of the vacuolar (H+)-ATPases.Archives of biochemistry and biophysics · 2008Review
- Analysis of the membrane topology of transmembrane segments in the C-terminal hydrophobic domain of the yeast vacuolar ATPase subunit a (Vph1p) by chemical modification.The Journal of biological chemistry · 2008Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The vacuolar H+-ATPase (V-ATPase) is one of the most fundamental enzymes in nature. It functions in almost every eukaryotic cell and energizes a wide variety of organelles and membranes. V-ATPase has a structure and mechanism of action similar to F-ATPase and several of their subunits probably evolved from common ancestors. In eukaryotic cells, F-ATPase is confined to the semiautonomous organelles, chloroplasts and mitochondria, which contain their own genes that encode some of the F-ATPase subunits. In contrast to F-ATPases, whose primary function in eukaryotic cells is to form ATP at the expense of the protonmotive force (pmf), V-ATPases function exclusively as ATP-dependent proton pumps. The pmf generated by V-ATPases in organelles and membranes of eukaryotic cells is utilized as a driving force for numerous secondary transport processes. It was the survival of the yeast mutant without the active enzyme and yeast genetics that allowed the identification of genuine subunits of the V-ATPase. It also revealed special properties of individual subunits, factors that are involved in the enzyme's biogenesis and assembly, as well as the involvement of V-ATPase in the secretory pathway, endocytosis, and respiration. It may be the insect V-ATPase that unconventionally resides in the plasma membrane of their midgut, that will give the first structure resolution of this complex.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.