ArticleBirth defects research. Part A, Clinical and molecular teratology2003
Joint laxity and the risk of clubfoot.
Article in Birth defects research. Part A, Clinical and molecular teratology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
7 citing papers in PubMed, 14 citations in OpenAlex.
- Tracing neurodevelopment and growth pattern in six-year-old children with idiopathic clubfoot: a national cohort study.BMC musculoskeletal disorders · 2025Article
- Collagen I in the Hip Capsule Plays a Role in Postoperative Clinical Function in Patients With Developmental Dysplasia of the Hip.Frontiers in pediatrics · 2022Article
- Objective analysis of intermediate-term outcome of the Ponseti technique: a review of the experience from Los Angeles.Annals of translational medicine · 2021Review
- Association between maternal age at conception and risk of idiopathic clubfoot.Acta orthopaedica · 2016Article
- Epidemiology of congenital idiopathic talipes equinovarus in Iowa, 1997-2005.American journal of medical genetics. Part A · 2010Article
- Motor ability in children treated for idiopathic clubfoot. A controlled pilot study.BMC pediatrics · 2009Article
- The association between idiopathic clubfoot and increased internal hip rotation.Clinical orthopaedics and related research · 2009Article
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4 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundClubfoot is a relatively common and potentially disabling birth defect. The etiology of clubfoot (talipes equinovarus [TEV]) is not known. Joint laxity, or hypermobility, is a suspected risk factor for congenital hip dislocation and clubfoot.
methodsWe conducted a case-control study of TEV in five western Washington counties. A total of 239 cases of TEV were identified from hospital and outpatient sources from 1986 to 1994. Controls (n = 356) were identified by random-digit dialing (RDD). Parents were interviewed over the telephone, and medical records were abstracted. In-person measurements of four joint laxity indices in parents and the index child were obtained.
resultsModerately elevated adjusted odds ratios (ORs) were found for extension > 90 degrees of the entire little finger, and extension of all four fingers to a position parallel to the forearm (OR = 1.6; 95% CI = 0.9-2.9; and OR = 1.7; CI = 1.1-2.5; respectively). No elevation in the OR was found for the wrist and elbow laxity measures. No consistent pattern of association between joint laxity measures in parents and an elevated OR of clubfoot among their children was found.
conclusionsThe results of this study suggest a role for joint laxity in the etiology of TEV.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.