ReviewMolecular and cellular biochemistry2003
Recent advances in molecular genetics of glaucoma.
Review in Molecular and cellular biochemistry, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 63 citations in OpenAlex.
- Estimating the age of the p.Cys433Arg variant in the MYOC gene in patients with primary open-angle glaucoma.PloS one · 2018Trial
- Integrative transcriptomic and proteomic analysis reveals CD9/ITGA4/PI3K-Akt axis mediates trabecular meshwork cell apoptosis in human glaucoma.Journal of cellular and molecular medicine · 2020Article
- A spectrum of CYP1B1 mutations associated with primary congenital glaucoma in families of Pakistani descent.Human genome variation · 2016Article
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- Screening of the LTBP2 gene in a north Indian population with primary congenital glaucoma.Molecular vision · 2013Article
- Contribution of the latent transforming growth factor-β binding protein 2 gene to etiology of primary open angle glaucoma and pseudoexfoliation syndrome.Molecular vision · 2013Article
- Screening of CYP1B1 and MYOC in Moroccan families with primary congenital glaucoma: three novel mutations in CYP1B1.Molecular vision · 2010Article
- Molecular complexity of primary open angle glaucoma: current concepts.Journal of genetics · 2009Review
- Contributions of MYOC and CYP1B1 mutations to JOAG.Molecular vision · 2008Article
- Screening of common CYP1B1 mutations in Iranian POAG patients using a microarray-based PrASE protocol.Molecular vision · 2008Article
- CYP1B1 mutation profile of Iranian primary congenital glaucoma patients and associated haplotypes.The Journal of molecular diagnostics : JMD · 2007Article
- Expression, purification, crystallization and preliminary X-ray analysis of the olfactomedin domain from the sea urchin cell-adhesion protein amassin.Acta crystallographica. Section F, Structural biology and crystallization communications · 2006Article
- Molecular cloning of the m-Golsyn gene and its expression in the mouse brain.Gene expression · 2006Article
- P.Gly61Glu and P.Arg368His Mutations in CYP1B1 that Cause Congenital Glaucoma may be Relatively Frequent in Certain Regions of Gilan Province, Iran.Journal of ophthalmic & vision researchArticle
- Glaucoma in iran and contributions of studies in iran to the understanding of the etiology of glaucoma.Journal of ophthalmic & vision researchReview
- Genetic Basis of Primary Angle Closure Glaucoma: The Role of Collagens and Extracellular Matrix.Journal of ophthalmic & vision researchArticle
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Glaucoma represents a heterogeneous group of optic neuropathies, with different genetic bases. It can affect all ages generally with a rise in intra-ocular pressure. Three major types of glaucoma have been reported: primary open angle glaucoma (POAG), primary acute closed angle glaucoma (PACG) and primary congenital glaucoma (PCG), as well as a few others associated with developmental abnormalities. In recent years impressive progress has been made in the molecular genetic studies of POAG and PCG. These include the discovery of three genes--Myocilin, Optineurin and CYP1B1--defects in which results in Mendelian transmission of glaucoma. Identification of single nucleotide polymorphisms in multiple other genes that are associated with glaucoma and alteration of drug sensitivity are enriching our knowledge regarding the complex nature of the disease. This review attempts to present the recent progress made in the molecular genetics of glaucoma.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.