Evidence map›Paper›PMID 14618647›Full record

ArticlePediatric pulmonology2003

Quality of life in adolescents with mild asthma.

Teal S Hallstrand, J Randall Curtis, Moira L Aitken, Sean D Sullivan

Open access · greenAbstract readComparative Study
In one paragraph

Article in Pediatric pulmonology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 78 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Trial
  4. Review
  5. Article
  6. Health-related quality of life profiles in adolescents and young adults with chronic conditions.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2023
    Article
  7. Article
  8. Article
  9. Review
  10. Quality of Life in Children with Asthma versus Healthy Children.Open access Macedonian journal of medical sciences · 2018
    Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Predicting quality of life in pediatric asthma: the role of emotional competence and personality.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2013
    Article
  18. Review
  19. Epithelial regulation of eicosanoid production in asthma.Pulmonary pharmacology & therapeutics · 2012
    Review
  20. Role of leukotrienes in exercise-induced bronchoconstriction.Current allergy and asthma reports · 2009
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Teal S HallstrandDivision of Pulmonary and Critical Care Medicine, Department of Medicine, University of Washington, Seattle, Washington 98195-6522, USA. tealh@u.washington.edu
J Randall Curtis
Moira L Aitken
Sean D Sullivan
University of Washington · US

Funding

AIRWAY INFLAMMATION IN EXERCISE-INDUCED ASTHMAK23HL004231 · NHLBI · UNIVERSITY OF WASHINGTON · PI HALLSTRAND, TEAL S · 2000 to 2004
$621k
Expression Studies of Myoson XZ01HL004231 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI SELLERS, JAMES R. · 1999 to 2008
$413k
Intramural NIH HHS Z01 HL004231NHLBI NIH HHS K23 HL004231
6 · The paper itself

Abstract

The majority of individuals with asthma have mild disease, often in conjunction with allergic rhinitis and exercise-induced bronchoconstriction (EIB). Although health-related quality-of-life (HRQoL) is reduced in moderate to severe asthma and allergic rhinitis, little is known about the effect of mild asthma, mild allergic rhinitis, and EIB on HRQoL outcomes. The objective of this study was to determine the effect of mild asthma, allergic rhinitis, and EIB on HRQoL. A cross-sectional study was conducted of 160 adolescent athletes participating in a screening program to detect EIB. Generic HRQoL was assessed with the teen version of the pediatric quality-of-life inventory (PedsQL). Prior diagnoses of asthma, allergic rhinitis, and EIB, and current symptoms of dyspnea during exercise and asthma, were recorded. Lung function and the presence of EIB were determined by spirometry before and after an exercise challenge test. Adolescent athletes with a prior physician diagnosis of asthma had a lower HRQoL scale summary score (P<0.01) and lower physical functioning, emotional functioning, and school functioning domain scores (P values, 0.01-0.02) in comparison to adolescent athletes with no prior diagnosis of these disorders. Athletes with a prior diagnosis of asthma reported dyspnea during exercise more frequently than did those without asthma (P<0.001). Adolescent athletes with dyspnea during exercise had a lower scale summary score, and lower physical functioning, general well-being, and emotional functioning domain scores (P values, 0.02-0.03). These data show that mild asthma and dyspnea without asthma significantly affect HRQoL. Symptoms of dyspnea during exercise are common in asthma and are associated with lower HRQoL. The clinical significance of these differences in HRQoL is unclear.

Indexed as

Quality of LifeAdolescentAsthmaAsthma, Exercise-InducedComorbidityCross-Sectional StudiesDyspneaFemaleHumansMaleReference ValuesRespiratory Function TestsRhinitis, Allergic, PerennialSpirometrySportsWashington

Identifiers

PMID14618647
PMCPMC2002508
OpenAlexW1976151388

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.