ReviewReproductive biology and endocrinology : RB&E2003
Tissue engineering and cell based therapies, from the bench to the clinic: the potential to replace, repair and regenerate.
Review in Reproductive biology and endocrinology : RB&E, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 150 citations in OpenAlex.
- Role of mesenchymal stem cell-derived exosomal non-coding RNAs in bone and bone-related disorders.World journal of stem cells · 2025Review
- Bioprinting Perfusable and Vascularized Skeletal Muscle Flaps for the Treatment of Volumetric Muscle Loss.Advanced healthcare materials · 2025Article
- Genetically engineered cellular nanoparticles for biomedical applications.Biomaterials · 2023Review
- In Vivo Efficacy of Neutrophil-Mediated Bone Regeneration Using a Rabbit Calvarial Defect Model.International journal of molecular sciences · 2021Article
- Applications of 3D Bioprinting in Tissue Engineering and Regenerative Medicine.Journal of clinical medicine · 2021Review
- Assessing the potential use of chitosan scaffolds for the sustained localized delivery of vitamin D.Saudi journal of biological sciences · 2021Article
- Basic Research on Tendon Repair: Strategies, Evaluation, and Development.Frontiers in medicine · 2021Review
- Pioneering Position of Iranian Scientists on Vital Pulp Therapy.Iranian endodontic journal · 2021Article
- Hair follicle stem cells differentiation into bone cells on collagen scaffold.Cell and tissue banking · 2020Article
- A Combination of Oxo-M and 4-PPBP as a potential regenerative therapeutics for tendon injury.Theranostics · 2019Article
- Omega-3 Fatty Acids Supplementation Differentially Modulates the SDF-1/CXCR-4 Cell Homing Axis in Hypertensive and Normotensive Rats.Nutrients · 2017Article
- PTH/SDF-1α cotherapy induces CD90+CD34- stromal cells migration and promotes tissue regeneration in a rat periodontal defect model.Scientific reports · 2016Article
- Intramuscular injection of bone marrow mononuclear cells contributes to bone repair following midpalatal expansion in rats.Molecular medicine reports · 2016Article
- Cell Therapy in Ischemic Heart Disease: Interventions That Modulate Cardiac Regeneration.Stem cells international · 2016Review
- Harnessing endogenous stem/progenitor cells for tendon regeneration.The Journal of clinical investigation · 2015Article
- Use of recombinant human stromal cell-derived factor 1α-loaded fibrin/hyaluronic acid hydrogel networks to achieve functional repair of full-thickness bovine articular cartilage via homing of chondrogenic progenitor cells.Arthritis & rheumatology (Hoboken, N.J.) · 2015Article
- In situ tissue regeneration: chemoattractants for endogenous stem cell recruitment.Tissue engineering. Part B, Reviews · 2014Review
- Article
- SDF-1 enhances wound healing of critical-sized calvarial defects beyond self-repair capacity.PloS one · 2014Article
- Biobanking for research in surgery: are surgeons in charge for advancing translational research or mere assistants in biomaterial and data preservation?Langenbeck's archives of surgery · 2013Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
The field of Regenerative Biology as it applies to Regenerative Medicine is an increasingly expanding area of research with hopes of providing therapeutic treatments for diseases and/or injuries that conventional medicines and even new biologic drug therapies cannot effectively treat. Extensive research in the area of Regenerative Medicine is focused on the development of cells, tissues and organs for the purpose of restoring function through transplantation. The general belief is that replacement, repair and restoration of function is best accomplished by cells, tissues or organs that can perform the appropriate physiologic/metabolic duties better than any mechanical device, recombinant protein therapeutic or chemical compound. Several strategies are currently being investigated and include, cell therapies derived from autologous primary cell isolates, cell therapies derived from established cell lines, cell therapies derived from a variety of stem cells, including bone marrow/mesenchymal stem cells, cord blood stem cells, embryonic stem cells, as well as cells tissues and organs from genetically modified animals. This mini-review is not meant to be exhaustive, but aims to highlight clinical applications for the four areas of research listed above and will address a few key advances and a few of the hurdles yet to be overcome as the technology and science improve the likelihood that Regenerative Medicine will become clinically routine.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.