Evidence map›Paper›PMID 14610049›Full record

ReviewThe Journal of cell biology2003

Traffic control: p120-catenin acts as a gatekeeper to control the fate of classical cadherins in mammalian cells.

Mark Peifer, Alpha S Yap

Open access · bronzeAbstract readCommentReview
In one paragraph

Review in The Journal of cell biology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 94 citations in OpenAlex.

  1. Review
  2. Cadherin Signaling in Cancer and Autoimmune Diseases.International journal of molecular sciences · 2021
    Review
  3. Review
  4. Article
  5. Article
  6. Integration of Cadherin Adhesion and Cytoskeleton atCold Spring Harbor perspectives in biology · 2017
    Review
  7. The mechanotransduction machinery at work at adherens junctions.Integrative biology : quantitative biosciences from nano to macro · 2015
    Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. The assembly and maintenance of epithelial junctions in C. elegans.Frontiers in bioscience (Landmark edition) · 2009
    Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 2 countries.

Mark PeiferDepartment of Biology and Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599-3280, USA. peifer@unc.edu
Alpha S Yap
University of North Carolina at Chapel Hill · USUniversity of Queensland · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Proteins of the p120 family have been implicated in the regulation of cadherin-based cell adhesion, but their relative importance in this process and their mechanism of action have remained less clear. Three papers in this issue suggest that p120 plays a key role in maintaining normal levels of cadherin in mammalian cells, and that it may do so by regulating cadherin trafficking (Chen et al., 2003; Davis et al., 2003; Xiao et al., 2003).

Indexed as

Adherens JunctionsAnimalsCadherinsCateninsCell AdhesionCell Adhesion MoleculesCell MembraneDelta CateninHumansMammalsPhosphoproteinsProtein TransportSignal TransductionCadherinsCateninsCell Adhesion MoleculesCTNND1 protein, humanDelta CateninPhosphoproteins

Identifiers

PMID14610049
PMCPMC2173635
OpenAlexW2040750859

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.