Evidence map›Paper›PMID 14609028›Full record

ReviewJournal of muscle research and cell motility2003

Smooth, slow and smart muscle motors.

Anders Arner, Mia Löfgren, Ingo Morano

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of muscle research and cell motility, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 36 citations in OpenAlex.

  1. The Contractile Machines of the Heart.Advances in experimental medicine and biology · 2024
    Review
  2. Tissue-specific expression of myosin phosphatase subunits and isoforms in smooth muscle of mice and humans.American journal of physiology. Regulatory, integrative and comparative physiology · 2022
    Article
  3. Signaling and metabolic properties of fast and slow smooth muscle types from mice.Pflugers Archiv : European journal of physiology · 2018
    Article
  4. Article
  5. Maximum shortening velocity of lymphatic muscle approaches that of striated muscle.American journal of physiology. Heart and circulatory physiology · 2013
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Regulation of the uterine contractile apparatus and cytoskeleton.Seminars in cell & developmental biology · 2007
    Review
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Anders ArnerDepartment of Physiological Sciences, Medical Faculty, Lund University, BMC F11, Tornavägen 10, SE-221 84 Lund, Sweden. Anders.Arner@mphy.lu.se
Mia Löfgren
Ingo Morano
Lund University · SEMax Delbrück Center · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Smooth muscle is a slow and economical muscle with a large variability in contractile properties. This review describes results regarding the relation between expression of myosin isoforms and the contraction of smooth muscle. The focus of the review is on studies of the organised contractile system in the smooth muscle tissue. The role of the myosin heavy chain variants formed by alternative splicing in the myosin heavy chain tail (SM1, SM2 isoforms) and head (SM-A SM-B isoforms) regions, as well as the role of essential light chains (LC17a, LC17b isoforms) for the variability of contractile properties are discussed. Smooth muscle also has the ability to alter its contractile properties in response to altered functional demands in vivo, e.g. during hypertrophic growth of urinary bladder, intestine, uterus and vessels and in response to altered hormone levels. These alterations involve changes in myosin expression and altered contractile kinetics. Non-muscle myosin has been shown to have a contractile function in some smooth muscle tissues and recent data on the kinetic properties of non-muscle myosin filaments in smooth muscle tissue are described.

Indexed as

Adenosine TriphosphateAnimalsGene Expression RegulationKineticsMolecular Motor ProteinsMuscle ContractionMuscle Fibers, Fast-TwitchMuscle Fibers, Slow-TwitchMuscle, SmoothMyosin Heavy ChainsMyosin Light ChainsNonmuscle Myosin Type IIBProtein IsoformsSmooth Muscle MyosinsAdenosine TriphosphateMolecular Motor ProteinsMyosin Heavy ChainsMyosin Light ChainsNonmuscle Myosin Type IIBnonmuscle myosin type IIB heavy chainProtein IsoformsSmooth Muscle Myosins

Identifiers

PMID14609028
OpenAlexW1698954587

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.