Evidence map›Paper›PMID 14609026›Full record

ReviewJournal of muscle research and cell motility2003

Random walks with thin filaments: application of in vitro motility assay to the study of actomyosin regulation.

Steven Marston

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of muscle research and cell motility, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Force Measurements From Myofibril to Filament.Frontiers in physiology · 2021
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 2 countries.

Steven MarstonImperial College London, NHLI Doverhouse Street, London SW3 6LY, UK. s.marston@ic.ac.uk
In-Q-Tel · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The in vitro motility devised by Kron and Spudich (Kron and Spudich, 1986; Kron et al., 1991) has proved a very valuable technique for studying the motor properties of myosin of all kinds but it is equally useful for the study of the thin filaments of muscle and their regulation. The movement of a population of thin filaments over immobilised myosin appears to be random but it does in fact yield a large amount of information about contractility and its regulation. The key to extracting useful information from in vitro motility assay experiments is the logical and comprehensive analysis of filament movements.

Indexed as

Actin CytoskeletonActomyosinAnimalsCalciumCalcium-Binding ProteinsCalmodulin-Binding ProteinsCalponinsCardiomyopathiesHumansImage Processing, Computer-AssistedMicrofilament ProteinsMicroscopy, FluorescenceMuscle ContractionMutationMyosin SubfragmentsTropomyosinActomyosinCalciumCalcium-Binding ProteinsCalmodulin-Binding ProteinsCalponinsMicrofilament ProteinsMyosin SubfragmentsTropomyosinTroponin

Identifiers

PMID14609026
OpenAlexW199045229

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.