ArticleWorld journal of gastroenterology2003
Organ failure associated with severe acute pancreatitis.
Article in World journal of gastroenterology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed, 70 citations in OpenAlex.
- Comparison of clinical outcomes between non-invasive ventilation and high-flow nasal cannula use in patients with acute pancreatitis.BMC pulmonary medicine · 2026Article
- Admission hematocrit and fluctuating blood urea nitrogen levels predict the efficacy of blood purification treatment in severe acute pancreatitis patients.Journal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2025Article
- Unraveling the Yellow Mystery: Severe Jaundice and Multisystem Collapse in a Returning Traveler.Cureus · 2025Article
- Early Prophylactic Anticoagulation and In-Hospital Mortality in Patients with Severe Acute Pancreatitis: A Retrospective Cohort Study.Open access emergency medicine : OAEM · 2025Article
- LRG1 inhibition promotes acute pancreatitis recovery by inducing cholecystokinin Type 1 receptor expression via Akt.Theranostics · 2025Article
- Free intraperitoneal air in infected pancreatic necrosis with intraperitoneal rupture: A rare presentation of a complex diseases.Clinical case reports · 2024Article
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- Medical imaging for pancreatic diseases: Prediction of severe acute pancreatitis complicated with acute respiratory distress syndrome.World journal of gastroenterology · 2022Article
- Emodin attenuates severe acute pancreatitis-associated acute lung injury by suppressing pancreatic exosome-mediated alveolar macrophage activation.Acta pharmaceutica Sinica. B · 2022Article
- Elevated serum ferritin levels are associated with severity and prognosis of severe acute pancreatitis: a preliminary cohort study.BMC gastroenterology · 2022Article
- Predictors and outcomes of acute respiratory failure in hospitalised patients with acute pancreatitis.Frontline gastroenterology · 2021Article
- Article
- Curcumin protects against acute renal injury by suppressing JAK2/STAT3 pathway in severe acute pancreatitis in rats.Experimental and therapeutic medicine · 2017Article
- Article
- Percutaneous Catheter Drainage in Infected Pancreatitis Necrosis: a Systematic Review.The Indian journal of surgery · 2016Article
- Hypotension in the first week of acute pancreatitis and APACHE II score predict development of infected pancreatic necrosis.Digestive diseases and sciences · 2015Article
- Changes of neuronal acetylcholine receptor alpha 7 of peritoneal macrophage in experimental acute pancreatitis treated by Chaiqin Chengqi Decoction ().Chinese journal of integrative medicine · 2014Article
- Severe acute pancreatitis: pathogenetic aspects and prognostic factors.World journal of gastroenterology · 2008Review
- Protective effects of baicalin and octreotide on multiple organ injury in severe acute pancreatitis.Digestive diseases and sciences · 2008Article
- Organ failure associated with acute pancreatitis in African-American and Hispanic patients.Journal of the National Medical Association · 2007Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimTo investigate the relationship between severe acute pancreatitis (SAP) and organ failure.
methodsClinical data of 74 cases of SAP from Jan. 1993 to Dec. 2002 were retrospectively reviewed, and the relationship between organ failure and age, gender, etiology, extent of necrosis, infection of necrosis and mortality was analyzed.
resultsA total of 47 patients (63.5%) showed organ failure, 20 patients (27.0%) multiple organ failure, whereas 27 patients (36.5%) with dysfunction of a single organ system. Pulmonary failure was the most common organ dysfunction (23.0%) among single organ failures. There were no significant differences in age, gender and gallstone pancreatitis among patients with or without organ failure (P>0.05). The incidence of organ failure in infected necrosis was not higher compared with sterile necrosis, and patients with increased amount of necrosis did not have an increased prevalence of organ failure (P>0.05). Patients with organ failure had a higher mortality rate compared with those without organ failure (P<0.05). The death of SAP was associated with multiple organ failure (P<0.005), pulmonary failure (P<0.005), cardiovascular dysfunction (P<0.05) and gastrointestinal dysfunction (P<0.05).
conclusionOrgan failure is common in patients with SAP, and patients with multiple organ failure and pulmonary failure have a higher mortality rate. Prevention and active treatment of organ failure can improve the outcome of patients with SAP.
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