ArticleJournal of clinical microbiology2003
Molecular epidemiology of Proteus mirabilis infections of the catheterized urinary tract.
Article in Journal of clinical microbiology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 79 citations in OpenAlex.
- Urinary bactericidal activity of extended-release ciprofloxacin (1,000 milligrams) versus levofloxacin (500 milligrams) in healthy volunteers receiving a single oral dose.Antimicrobial agents and chemotherapy · 2006Trial
- Evaluation of Bcr/cflA Targeted Efflux Inhibitory Potential of 2-Hydroxy-4-Methoxybenzaldehyde AgainstIndian journal of microbiology · 2025Article
- Perfluoropolyether-incorporated polyurethane with enhanced antibacterial and anti-adhesive activities for combating catheter-induced infection.RSC advances · 2024Article
- Article
- Silicone Foley catheters impregnated with microbial indole derivatives inhibit crystalline biofilm formation byFrontiers in cellular and infection microbiology · 2022Article
- Carbapenemase production among less-common Enterobacterales genera: 10 US sites, 2018.JAC-antimicrobial resistance · 2021Article
- From the Urinary Catheter to the Prevalence of Three Classes of Integrons,BioMed research international · 2021Article
- Ynt is the primary nickel import system used by Proteus mirabilis and specifically contributes to fitness by supplying nickel for urease activity.Molecular microbiology · 2020Article
- Explication of the Potential of 2-Hydroxy-4-Methoxybenzaldehyde in Hampering UropathogenicFrontiers in microbiology · 2019Article
- Pathogenesis ofEcoSal Plus · 2018Review
- Review of Catheter-Associated Urinary Tract Infections andJournal of healthcare engineering · 2018Review
- Imipenem-resistant Gram-negative bacterial isolates carried by persons upon medical examination in Korea.Journal of microbiology (Seoul, Korea) · 2017Article
- Clinical and Molecular Characterization of Community-Onset Urinary Tract Infections Due to Extended-Spectrum Cephalosporin-Resistant Enterobacteriaceae.Infection control and hospital epidemiology · 2016Article
- IMP-27, a Unique Metallo-β-Lactamase Identified in Geographically Distinct Isolates of Proteus mirabilis.Antimicrobial agents and chemotherapy · 2016Article
- Proteus mirabilis fimbriae- and urease-dependent clusters assemble in an extracellular niche to initiate bladder stone formation.Proceedings of the National Academy of Sciences of the United States of America · 2016Article
- Bacteriophage Can Prevent Encrustation and Blockage of Urinary Catheters by Proteus mirabilis.Antimicrobial agents and chemotherapy · 2015Article
- Elucidating the genetic basis of crystalline biofilm formation in Proteus mirabilis.Infection and immunity · 2014Article
- Prevalence and molecular epidemiology of acquired AmpC β-lactamases and carbapenemases in Enterobacteriaceae isolates from 35 hospitals in Spain.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2013Article
- Merging mythology and morphology: the multifaceted lifestyle of Proteus mirabilis.Nature reviews. Microbiology · 2012Review
- Rapid and sensitive detection of major uropathogens in a single-pot multiplex PCR assay.Current microbiology · 2012Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Proteus mirabilis compromises the care of many patients undergoing long-term indwelling bladder catheterization. It forms crystalline bacterial biofilms in catheters which block the flow of urine, causing either incontinence due to leakage or painful distention of the bladder due to urinary retention. If it is not dealt with, catheter blockage can lead to pyelonephritis and septicemia. We have examined the epidemiology of catheter-associated P. mirabilis infections by use of pulsed-field gel electrophoresis (PFGE) of NotI restriction enzyme digests of bacterial DNA. This technique was shown to be more discriminatory than the classical phenotypic Dienes typing technique. We demonstrated that each of 42 isolates from diverse environmental sources and 10 of 12 isolates from blood, wound swabs, and mid-stream urine samples of hospitalized patients had distinct genotypes. Examination of a set of 55 isolates of P. mirabilis, each from a different clinical or environmental source, identified 49 distinct genotypes and 43 Dienes types. The index of discrimination was 0.993 for the PFGE method and 0.988 for the Dienes method. Applying the PFGE method to isolates from catheter-associated urinary tract infections confirmed that the strains present in the crystalline catheter biofilms were identical to those isolated from the same patient's urine. An analysis of samples taken during a prospective study of infections in catheterized nursing home patients revealed that a single genotype of P. mirabilis can persist in the urinary tract despite many changes of catheter, periods of noncatheterization, and antibiotic therapy.
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