ArticleNucleic acids research2003
Viral and microbial genotyping by a combination of multiplex competitive hybridization and specific extension followed by hybridization to generic tag arrays.
Article in Nucleic acids research, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 32 citations in OpenAlex.
- Article
- Identification of microbial DNA in human cancer.BMC medical genomics · 2009Article
- An in vitro selection scheme for oligonucleotide probes to discriminate between closely related DNA sequences.Nucleic acids research · 2007Article
- Comparison of PrASE and Pyrosequencing for SNP Genotyping.BMC genomics · 2006Article
- PathogenMIPer: a tool for the design of molecular inversion probes to detect multiple pathogens.BMC bioinformatics · 2006Article
- Competitive enzymatic reaction to control allele-specific extensions.Nucleic acids research · 2005Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Detection and identification of microbial pathogens are important for disease diagnosis, treatment and prophylaxis measurements. By introducing an innovative technique, we show a robust, reliable and accurate microarray-based method for identification of microbial pathogens. The technique utilizes a unique combination of multiplex competitive hybridization, which enhances hybridization accuracy of oligonucleotides to the specific target, and apyrase-mediated allele-specific extension, which improves specific extension. As a model system, different clinically relevant human papillomaviruses were selected for this study. The method generated accurate results and proves to be promising for specific and correct microbial and viral typing.
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Registered trials
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