ArticleProceedings of the National Academy of Sciences of the United States of America2003
Multiple oscillators regulate circadian gene expression in Neurospora.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
64 citing papers in PubMed.
- Circadian Biology in Parasites: Beyond Known Mechanisms.Annual review of microbiology · 2025Review
- Individual peroxiredoxin or Tor pathway components are not required for circadian clock function in Neurospora crassa.Fungal biology · 2025Article
- Circadian regulation of the transcriptome in a complex polyploid crop.PLoS biology · 2022Article
- Principles of the animal molecular clock learned from Neurospora.The European journal of neuroscience · 2020Review
- No Evidence That Homologs of Key Circadian Clock Genes Direct Circadian Programs of Development or mRNA Abundance inFrontiers in microbiology · 2020Article
- A component of the TOR (Target Of Rapamycin) nutrient-sensing pathway plays a role in circadian rhythmicity in Neurospora crassa.PLoS genetics · 2018Article
- The role of the circadian clock system in physiology.Pflugers Archiv : European journal of physiology · 2018Review
- A HAD family phosphatase CSP-6 regulates the circadian output pathway in Neurospora crassa.PLoS genetics · 2018Article
- Making Time: Conservation of Biological Clocks from Fungi to Animals.Microbiology spectrum · 2017Review
- The Neurospora Transcription Factor ADV-1 Transduces Light Signals and Temporal Information to Control Rhythmic Expression of Genes Involved in Cell Fusion.G3 (Bethesda, Md.) · 2017Article
- Natural Variation of the Circadian Clock in Neurospora.Advances in genetics · 2017Review
- Article
- Synchronizing stochastic circadian oscillators in single cells of Neurospora crassa.Scientific reports · 2016Article
- Modulation of Circadian Gene Expression and Metabolic Compensation by the RCO-1 Corepressor of Neurospora crassa.Genetics · 2016Article
- The circadian system as an organizer of metabolism.Fungal genetics and biology : FG & B · 2016Review
- Analysis of Circadian Rhythms in the Basal Filamentous Ascomycete Pyronema confluens.G3 (Bethesda, Md.) · 2015Article
- Dawn- and dusk-phased circadian transcription rhythms coordinate anabolic and catabolic functions in Neurospora.BMC biology · 2015Article
- Article
- Circadian Control of Global Transcription.BioMed research international · 2015Review
- Analysis of clock-regulated genes in Neurospora reveals widespread posttranscriptional control of metabolic potential.Proceedings of the National Academy of Sciences of the United States of America · 2014Article
4 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
High-density microarrays were used to profile circadian gene expression in Neurospora crassa cultures grown in constant darkness. We identified 145 clock-controlled genes (ccgs). The ccgs peaked in mRNA accumulation at all phases of the day, with the majority peaking in the late night to early morning. The predicted or known functions of the ccgs demonstrate that the clock contributes to a wide range of cellular processes, including cell signaling, development, metabolism, and stress responses. Although the period of rhythm of most of the ccgs was found to depend on the well characterized frequency (FRQ)-based oscillator, three ccgs appeared to have a rhythm that was significantly short in the long period (29-h) frq7 mutant strain. These ccgs accumulate mRNA rhythmically with a circadian period in a frq-null strain, confirming the existence of a second oscillator in N. crassa.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.