Evidence map›Paper›PMID 14594572›Full record

ReviewCurrent hypertension reports2003

Impact of female hormones on blood pressure: review of potential mechanisms and clinical studies.

Jane Morley Kotchen, Theodore A Kotchen

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current hypertension reports, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 18 citations in OpenAlex.

  1. Trial
  2. Elevated blood pressure, stroke volume, and vascular tone in young women who use oral contraception.International journal of psychophysiology : official journal of the International Organization of Psychophysiology · 2025
    Article
  3. Hypertension in Women.Frontiers in cardiovascular medicine · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jane Morley KotchenDivision of Epidemiology, Health Policy Institute, Medical College of Wisconsin, 8701 Watertown Plank Road, Milwaukee, WI 53226, USA. jkotchen@mcw.edu
Theodore A Kotchen
Medical College of Wisconsin · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent studies, it has been found that postmenopausal hormonal therapy is associated with an increased incidence of cardiovascular disease. Experimental studies suggest several potential mechanisms by which estrogens might decrease blood pressures, and estrogen administration attenuates hypertension in several animal models. In humans, although oral contraceptive agents are frequently associated with increases in blood pressure, blood pressure was not increased or was minimally increased in prospective clinical trials of hormone therapy in postmenopausal women. These observations suggest that the excess rates of cardiovascular disease are not caused by increased blood pressure.

Indexed as

AnimalsBlood PressureCardiovascular DiseasesContraceptive Agents, FemaleEndothelium, VascularEstrogen Replacement TherapyEstrogensFemaleHormonesHumansMaleMuscle, Smooth, VascularProgesteroneRisk AssessmentVascular ResistanceContraceptive Agents, FemaleEstrogensHormonesProgesterone

Identifiers

PMID14594572
OpenAlexW1991757065

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.