Evidence map›Paper›PMID 14588074›Full record

ReviewReproductive biology and endocrinology : RB&E2003

The role of protein elongation factor eEF1A2 in ovarian cancer.

Jonathan M Lee

Open access · goldAbstract readComparative StudyReview
In one paragraph

Review in Reproductive biology and endocrinology : RB&E, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 52 citations in OpenAlex.

  1. Review
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  10. Translational control in cancer etiology.Cold Spring Harbor perspectives in biology · 2013
    Review
  11. Article
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  14. The cancerous translation apparatus.Current opinion in genetics & development · 2011
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Jonathan M LeeHamilton Regional Cancer Centre, 699 Concession Street, Hamilton, Ontario, Canada L8V 5C2. jonathan.lee@hrcc.on.ca
Cancer Care Ontario · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Frequent gains of chromosome 20q12-13 in ovarian tumors indicate that at least one important oncogene is found at that locus. One of the genes there is EEF1A2, which maps to 20q13.3 and encodes protein elongation factor eEF1A2. This review will focus on recent evidence indicating that EEF1A2 is an important ovarian oncogene and that the protein elongation network can activate tumorigenesis and inhibit apoptosis.

Indexed as

ApoptosisCell Transformation, NeoplasticChromosome AberrationsChromosomes, Human, Pair 20FemaleGene AmplificationHumansIn Situ Hybridization, FluorescenceNucleic Acid HybridizationOncogenesOvarian NeoplasmsPeptide Chain Elongation, TranslationalPeptide Elongation Factor 1TrisomyEEF1A2 protein, humanPeptide Elongation Factor 1

Identifiers

PMID14588074
PMCPMC239897
OpenAlexW2149186189

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.