ArticleClinical and experimental immunology1992
Kinetics of lymphocyte subsets from peripheral blood during a Plasmodium falciparum malaria attack.
Article in Clinical and experimental immunology, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Performance of Interferon-Gamma and IP-10 Release Assays for Diagnosing Latent Tuberculosis Infections in Patients with Concurrent Malaria in Tanzania.The American journal of tropical medicine and hygiene · 2016Article
- The Immunologic Complexity of Growing Up with Malaria--Is Scientific Understanding Coming of Age?Clinical and vaccine immunology : CVI · 2016Article
- Lymphocyte Perturbations in Malawian Children with Severe and Uncomplicated Malaria.Clinical and vaccine immunology : CVI · 2015Article
- Variable effect of co-infection on the HIV infectivity: within-host dynamics and epidemiological significance.Theoretical biology & medical modelling · 2012Article
- Pneumococcal infections in humans are associated with increased apoptosis and trafficking of type 1 cytokine-producing T cells.Infection and immunity · 2002Article
- Cytokine production and apoptosis among T cells from patients under treatment for Plasmodium falciparum malaria.Clinical and experimental immunology · 2002Article
- Malaria infection induces rapid elevation of the soluble Fas ligand level in serum and subsequent T lymphocytopenia: possible factors responsible for the differences in susceptibility of two species of Macaca monkeys to Plasmodium coatneyi infection.Infection and immunity · 2000Article
- Rapid reemergence of T cells into peripheral circulation following treatment of severe and uncomplicated Plasmodium falciparum malaria.Infection and immunity · 1997Article
- The gamma/delta T-cell response to Plasmodium falciparum malaria in a population in which malaria is endemic.Infection and immunity · 1996Article
- Article
- Expression of the IL-1 receptor discriminates Th2 from Th1 cloned CD4+ T cells specific for Plasmodium chabaudi.Immunology · 1994Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Variations of lymphocyte subsets were followed longitudinally in 16 patients during an acute falciparum malaria attack. Before treatment, lymphocyte numbers were highly reduced, but the subset distribution was similar to that of healthy individuals. After parasite clearance, lymphocyte counts were normalized and the subset distribution was unchanged. This led to a normalization of all the absolute counts of lymphocyte subsets, except CD8+. The fast normalization of lymphocyte counts suggests that the initial decrease in lymphocyte numbers may reflect sequestration. Magnitude and kinetics of this variation were not related to parasite density or to severity of the attack. Activated T cells (CD3+HLA-DR+) were fewer in African than in European patients, suggesting the importance of the past exposure to malaria parasites in reallocation phenomena. These variations in lymphocyte numbers must be taken into account in the design and the analysis of cellular investigations in patients experiencing a falciparum malaria attack.
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