ReviewWorld journal of urology2003
Androgens and prostate cancer.
Review in World journal of urology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- Review
- Tomatoes, Lycopene, and Prostate Cancer: What Have We Learned from Experimental Models?The Journal of nutrition · 2022Review
- 5α-reductase 1 mRNA levels are positively correlated with TRAMP mouse prostate most severe lesion scores.PloS one · 2017Article
- Role of miRNA let-7 and its major targets in prostate cancer.BioMed research international · 2014Review
- Behavioral stress accelerates prostate cancer development in mice.The Journal of clinical investigation · 2013Article
- Hypoxic tumor kinase signaling mediated by STAT5A in development of castration-resistant prostate cancer.PloS one · 2013Article
- Bioglycans and natural glycosides as a promising research topic in bioorganic chemistriy.Acta naturae · 2010Article
- Does prolactin induce apoptosis? Evidences in a prostate cancer in vitro model.Journal of endocrinological investigation · 2010Article
- The cancer-related Runx2 protein enhances cell growth and responses to androgen and TGFbeta in prostate cancer cells.Journal of cellular biochemistry · 2010Article
- Differential effects of resveratrol on androgen-responsive LNCaP human prostate cancer cells in vitro and in vivo.Carcinogenesis · 2008Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Over 60 years ago Huggins and Hodges demonstrated the importance of androgens and prostate cancer. Since then, significant research has revealed that this relationship is multi-faceted and is interwoven with different signaling cascades and protein coactivators. The complex interrelationship between hormone and cancer is best exemplified by the recurrence and progression of prostate cancer after hormonal therapy to a lethally resistant phenotype despite initially encouraging therapeutic responses. If we are to significantly improve survival with novel therapies, further understanding of the emergence of this resistant phenotype is essential. The purpose of this article is to review the mechanisms of androgen action and its relation to hormonal therapy and mechanisms of hormonal resistance.
Indexed as
Identifiers
14586548What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.