Evidence map›Paper›PMID 14581576›Full record

ArticleJournal of virology2003

A bipartite late-budding domain in human immunodeficiency virus type 1.

Juan Martin-Serrano, Paul D Bieniasz

Open access · greenAbstract read
In one paragraph

Article in Journal of virology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
1.7field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 56 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. The role of cellular factors in promoting HIV budding.Journal of molecular biology · 2011
    Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Juan Martin-SerranoAaron Diamond AIDS Research Center, New York, New York, USA.
Paul D Bieniasz
Aaron Diamond AIDS Research Center · USRockefeller University · US

Funding

Mechanism of Action of Retroviral Late-Budding DomainsR01AI052774 · NIAID · AARON DIAMOND AIDS RESEARCH CENTER · PI BIENIASZ, PAUL D. · 2002 to 2011
$3.4M
NIAID NIH HHS R01 AI052774NIAID NIH HHS R01 AI52774
6 · The paper itself

Abstract

Human immunodeficiency virus type 1 (HIV-1) encodes a PTAP motif within the p6 domain of Gag that recruits Tsg101 and associated factors to facilitate virion budding. In this study, we use trans-complementation assays to demonstrate that the PTAP motif acts synergistically with additional p6 sequences to mediate the formation of infectious extracellular HIV-1 virions. These studies suggest that Tsg101 recruitment is necessary but not sufficient to account for late-budding activity exhibited by HIV-1 p6.

Indexed as

Amino Acid MotifsGene Products, gagHIV-1UbiquitinVirionGene Products, gagUbiquitin

Identifiers

PMID14581576
PMCPMC254264
OpenAlexW2105254705

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.