ReviewBreast cancer research : BCR2003
The diagnosis and management of pre-invasive breast disease: genetic alterations in pre-invasive lesions.
Review in Breast cancer research : BCR, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
39 citing papers in PubMed, 141 citations in OpenAlex.
- Unsupervised representation learning of chromatin images identifies changes in cell state and tissue organization in DCIS.Nature communications · 2024Article
- Review
- miR-301b-3p Regulates Breast Cancer Cell Proliferation, Migration, and Invasion by Targeting NR3C2.Journal of oncology · 2021Article
- Mutational profiling of micro-dissected pre-malignant lesions from archived specimens.BMC medical genomics · 2020Article
- The predictive value of calcification for the grading of ductal carcinoma in situ in Chinese patients.Medicine · 2020Observational
- Clinicopathological Characteristics ofInternational journal of medical sciences · 2020Observational
- TZAP Mutation Leads to Poor Prognosis of Patients with Breast CancerMedicina (Kaunas, Lithuania) · 2019Article
- Downregulation of miR-505 promotes cell proliferation, migration and invasion, and predicts poor prognosis in breast cancer.Oncology letters · 2019Article
- Intratumoral Heterogeneity in Ductal Carcinoma In Situ: Chaos and Consequence.Journal of mammary gland biology and neoplasia · 2018Review
- Clinicopathologic features of invasive metaplastic and micropapillary breast carcinoma: comparison with invasive ductal carcinoma of breast.BMC research notes · 2018Article
- Incidental Findings in Reduction Mammoplasty Specimens in Patients with No Prior History of Breast Cancer. An Analysis of 783 Specimens.Pathology oncology research : POR · 2018Article
- miR-433 inhibits breast cancer cell growth via the MAPK signaling pathway by targeting Rap1a.International journal of biological sciences · 2018Article
- MicroRNA-494 inhibits breast cancer progression by directly targeting PAK1.Cell death & disease · 2017Article
- Genome evolution in ductal carcinoma in situ: invasion of the clones.The Journal of pathology · 2017Review
- Gene expression profiling of mammary glands at an early stage of DMBA-induced carcinogenesis in the female Sprague-Dawley rat.European journal of oncology = Giornale europeo di oncologia · 2016Article
- Appraisal of the technologies and review of the genomic landscape of ductal carcinoma in situ of the breast.Breast cancer research : BCR · 2015Review
- Article
- Intraductal proliferative lesions of the breast-terminology and biology matter: premalignant lesions or preinvasive cancer?International journal of surgical oncology · 2012Article
- A mouse mammary tumor virus env-like exogenous sequence is strictly related to progression of human sporadic breast carcinoma.The American journal of pathology · 2011Article
- Comparative analysis of loss of heterozygosity and expression profile in normal tissue, DCIS and invasive breast cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The development of modern molecular genetic techniques has allowed breast cancer researchers to clarify the multistep model of breast carcinogenesis. Laser capture microdissection coupled with comparative genomic hybridisation and/or loss-of-heterozygosity methods have confirmed that many pre-invasive lesions of the breast harbour chromosomal abnormalities at loci known to be altered in invasive breast carcinomas. Current data do not provide strong evidence for ductal hyperplasia of usual type as a precursor lesion, although some are monoclonal proliferations; however, atypical hyperplasia and in situ carcinoma appear to be nonobligate precursors. We review current knowledge and the contribution of molecular genetics in the understanding of breast cancer precursors and pre-invasive lesions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.