ArticleAntimicrobial agents and chemotherapy2003
First Streptococcus agalactiae isolates highly resistant to quinolones, with point mutations in gyrA and parC.
Article in Antimicrobial agents and chemotherapy, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed, 92 citations in OpenAlex.
- Genetic Determinants and Clonal Composition of Levofloxacin-ResistantAntibiotics (Basel, Switzerland) · 2025Article
- Characterization of Penicillin-Non-Susceptible, Multidrug-Resistant Streptococcus agalactiae Using Whole-Genome Sequencing.Current microbiology · 2025Article
- Genetic Mechanisms of Antimicrobial Non-Susceptibility to Novel Fluoroquinolone Delafloxacin Among Bulgarian Clinical Isolates ofCurrent issues in molecular biology · 2025Article
- Retropharyngeal abscess caused byIDCases · 2025Article
- TwoFrontiers in microbiology · 2025Article
- Comparative genomics analysis of Streptococcus iniae isolated from Trachinotus ovatus: novel insight into antimicrobial resistance and virulence differentiation.BMC genomics · 2023Article
- Molecular Epidemiology of Group B Streptococci in Lithuania Identifies Multi-Drug Resistant Clones and Sporadic ST1 Serotypes Ia and Ib.Pathogens (Basel, Switzerland) · 2022Article
- Antimicrobial Resistance among Beta-HemolyticAntibiotics (Basel, Switzerland) · 2021Review
- Molecular subtyping and antimicrobial susceptibility ofJournal of veterinary science · 2020Article
- Endogenous endophthalmitis caused by group B streptococcus; case reports and review of 35 reported cases.BMC ophthalmology · 2020Review
- Changing Epidemiology of Group B Streptococcus Susceptibility to Fluoroquinolones and Aminoglycosides in France.Antimicrobial agents and chemotherapy · 2016Article
- Molecular Characteristics of Group B Streptococci Isolated from Adults with Invasive Infections in Japan.Journal of clinical microbiology · 2016Article
- Fluoroquinolone Resistance among Clonal Complex 1 Group B Streptococcus Strains.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2016Article
- In Vitro Activity of AZD0914, a Novel Bacterial DNA Gyrase/Topoisomerase IV Inhibitor, against Clinically Relevant Gram-Positive and Fastidious Gram-Negative Pathogens.Antimicrobial agents and chemotherapy · 2015Article
- Emergence of the first levofloxacin-resistant strains of Streptococcus agalactiae isolated in Italy.Antimicrobial agents and chemotherapy · 2015Article
- Association of mutation patterns in GyrA and ParC genes with quinolone resistance levels in lactic acid bacteria.The Journal of antibiotics · 2015Article
- Article
- Characterization of multidrug-resistant group B streptococci with reduced penicillin susceptibility forming small non-Beta-hemolytic colonies on sheep blood agar plates.Journal of clinical microbiology · 2014Article
- Genetic diversity and antimicrobial resistance in Streptococcus agalactiae strains recovered from female carriers in the Bucharest area.Memorias do Instituto Oswaldo Cruz · 2014Article
- Horizontal gene transfer and recombination in Streptococcus dysgalactiae subsp. equisimilis.Frontiers in microbiology · 2014Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Three isolates of Streptococcus agalactiae highly resistant to multiple fluoroquinolones were isolated in Japan. Compared with susceptible strains of S. agalactiae, these quinolone-resistant strains had double point mutations within the quinolone resistance-determining regions of gyrA and parC; Ser-81 was changed to Leu (TCA --> TTA) in the amino acid sequence deduced from gyrA, and Ser-79 was changed to Phe (TCC --> TTC) in the amino acid sequence deduced from parC. Comparative sequence analysis revealed the possibility of gene transfer between S. agalactiae and another beta-hemolytic streptococcus, Streptococcus difficile.
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