Trial reportJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
Stress-related variations in left ventricular function as assessed with gated myocardial perfusion SPECT.
Trial report in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 25 citations in OpenAlex.
- Prognostic implications of post-stress ejection fraction decrease detected by gated SPECT in the absence of stress-induced perfusion abnormalities.European journal of nuclear medicine and molecular imaging · 2011Trial
- Single-photon emission computed tomography as a fundamental tool in evaluation of myocardial reparation and regeneration therapies.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2022Review
- Better characterization of dipyridamole-induced myocardial stunning by systolic wall thickening. A gated perfusion SPECT study.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
- Additional value of systolic wall thickening in myocardial stunning evaluated by stress-rest gated perfusion SPECT.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2019Article
- Left ventricular function in response to dipyridamole stress: head-to-head comparison betweenEuropean journal of nuclear medicine and molecular imaging · 2017Article
- Gated cardiac SPECT: can it be used for serial assessment of left ventricular function in oncology patients?Nuclear medicine communications · 2013Article
- Post-stress left ventricular ejection fraction drop in patients with diabetes: a gated myocardial perfusion imaging study.BMC cardiovascular disorders · 2013Article
- Relationship between infarct size and severity measured by gated SPECT and long-term left ventricular remodelling after acute myocardial infarction.European journal of nuclear medicine and molecular imaging · 2011Article
- Reliability of myocardial perfusion gated SPECT for the reproducible evaluation of resting left ventricular functional parameters in long-term follow-up.European journal of nuclear medicine and molecular imaging · 2010Article
- The expanding role of left ventricular functional assessment using gated myocardial perfusion SPECT: the supporting actor is stealing the scene.European journal of nuclear medicine and molecular imaging · 2007Review
- Serial assessment of left ventricular function in various patient groups with Tl-201 gated myocardial perfusion SPECT.Radiation medicine · 2007Article
- Multicenter intercomparison assessment of consistency of left ventricular function from a gated cardiac SPECT phantom.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2006Article
- Differences in left ventricular ejection fraction and volumes measured at rest and poststress by gated sestamibi SPECT.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2006Article
- Performance of thallium-201 electrocardiography-gated myocardial perfusion single photon emission computed tomography to assess left ventricular function.The Kaohsiung journal of medical sciences · 2005Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThere is inconsistency in reported patient characteristics associated with differences in basal and poststress left ventricular function (delta ejection fraction [DeltaEF]) assessed by gated single photon emission computed tomography (SPECT). This inconsistency may therefore hamper adequate interpretation. In this study we first determined the reproducibility of serial gated SPECT-assessed left ventricular function. Second, we determined whether left ventricular ejection fraction (LVEF) assessed directly after stress reflects basal LVEF and, if not, what patient characteristics were associated with this discrepancy in LVEF. METHODS AND
resultsSerial reproducibility of technetium 99m tetrofosmin gated SPECT-assessed LVEF in 22 patients showed a mean difference between two sequential measurements at rest of 0.09% EF units, with a 95% limit of agreement (2 SDs) at 5.8% EF units. In 229 patients Tc-99m tetrofosmin gated SPECT was performed after stress and at rest. Independent predictors of DeltaEF were the presence of scintigraphically proven ischemia (standardized coefficient, -1.256; P =.003) and difference in heart rate at the time of acquisition (standardized coefficient, 0.121; P =.001).
conclusionsGated SPECT-assessed LVEF at rest is reproducible under standard clinical conditions. However, LVEF assessed after stress does not represent LVEF at rest in patients with scintigraphically proven ischemia and in patients with increased heart rate after stress compared with heart rate at rest.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.