ArticleImmunogenetics2003
Physical and genetic mapping of the rainbow trout major histocompatibility regions: evidence for duplication of the class I region.
Article in Immunogenetics, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed, 85 citations in OpenAlex.
- ATP-Binding Cassette Transporters: Snap-on Complexes?Sub-cellular biochemistry · 2022Article
- Review
- Comparative genome analyses reveal distinct structure in the saltwater crocodile MHC.PloS one · 2014Article
- Assignment of Chinook salmon (Oncorhynchus tshawytscha) linkage groups to specific chromosomes reveals a karyotype with multiple rearrangements of the chromosome arms of rainbow trout (Oncorhynchus mykiss).G3 (Bethesda, Md.) · 2013Article
- Selection and phylogenetics of salmonid MHC class I: wild brown trout (Salmo trutta) differ from a non-native introduced strain.PloS one · 2013Article
- Article
- Genetic resistance to rhabdovirus infection in teleost fish is paralleled to the derived cell resistance status.PloS one · 2012Article
- Primordial linkage of β2-microglobulin to the MHC.Journal of immunology (Baltimore, Md. : 1950) · 2011Article
- Molecular modeling of class I and II alleles of the major histocompatibility complex in Salmo salar.Journal of computer-aided molecular design · 2010Article
- Comprehensive analysis of MHC class I genes from the U-, S-, and Z-lineages in Atlantic salmon.BMC genomics · 2010Article
- Article
- A first generation BAC-based physical map of the rainbow trout genome.BMC genomics · 2009Article
- Comparative genomics and evolution of conserved noncoding elements (CNE) in rainbow trout.BMC genomics · 2009Article
- Multiple expressed MHC class II loci in salmonids; details of one non-classical region in Atlantic salmon (Salmo salar).BMC genomics · 2008Article
- Genomic organization of duplicated major histocompatibility complex class I regions in Atlantic salmon (Salmo salar).BMC genomics · 2007Article
- Gene duplication, allelic diversity, selection processes and adaptive value of MHC class II DRB genes of the bank vole, Clethrionomys glareolus.Immunogenetics · 2007Article
- Contrasting mode of evolution between the MHC class I genomic region and class II region in the three-spined stickleback (Gasterosteus aculeatus L.; Gasterosteidae: Teleostei).Immunogenetics · 2007Article
- A type I and type II microsatellite linkage map of rainbow trout (Oncorhynchus mykiss) with presumptive coverage of all chromosome arms.BMC genomics · 2006Article
- Article
- The salmonid MHC class I: more ancient loci uncovered.Immunogenetics · 2006Article
Corrections and comments
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Authors and funding
9 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
One of the most unexpected discoveries in MHC genetics came from studies dealing with the teleost MHC. Initially discovered in zebrafish, the MHC class I and II regions of all bony fish are not linked. Previous segregation analysis in trout suggested that the class I and II regions reside on completely different chromosomes. To learn more about MHC genomics in trout, we have isolated BAC clones harboring class Ia and Ib loci, a single BAC clone containing an MH class II gene ( DAB), as well as BAC clones containing the ABCB2 gene. Upon PCR and sequence confirmation, BAC clones were labeled and used as probes for in situ hybridization on rainbow trout metaphase chromosomes for determination of the physical locations of the trout MH regions. Finally, SNPs, RFLPs, and microsatellites found within the BAC clones allowed for these regions to be assigned to specific linkage groups on the OSU x Hotcreek (HC) and OSU x Arlee (ARL) genetic linkage maps. Our data demonstrate that the trout MH regions are located on at least four different chromosomes and the corresponding linkage groups, while also providing direct evidence for the partial duplication of the MH class I region in trout.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.