ArticleBMJ (Clinical research ed.)2003
Prognosis of angina with and without a diagnosis: 11 year follow up in the Whitehall II prospective cohort study.
Article in BMJ (Clinical research ed.), 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed, 81 citations in OpenAlex.
- Favourable long term prognosis in stable angina pectoris: an extended follow up of the angina prognosis study in Stockholm (APSIS).Heart (British Cardiac Society) · 2006Trial
- Evaluating Ischemic Heart Disease in Women: Focus on Angina With Nonobstructive Coronary Arteries (ANOCA).Journal of the Society for Cardiovascular Angiography & Interventions · 2024Review
- Long-Term Cardiovascular Risk and Management of Patients Recorded in Primary Care With Unattributed Chest Pain: An Electronic Health Record Study.Journal of the American Heart Association · 2022Article
- Article
- Integrated screening and treatment services for HIV, hypertension and diabetes in Kenya: assessing the epidemiological impact and cost-effectiveness from a national and regional perspective.Journal of the International AIDS Society · 2020Article
- Effect of coexisting vascular disease on long-term risk of recurrent events after TIA or stroke.Neurology · 2019Article
- Cost-effectiveness of risk stratified medication management for reducing premature cardiovascular mortality in Kenya.PloS one · 2019Article
- Validation of a Cardiovascular Disease Policy Microsimulation Model Using Both Survival and Receiver Operating Characteristic Curves.Medical decision making : an international journal of the Society for Medical Decision Making · 2017Article
- Prognosis of undiagnosed chest pain: linked electronic health record cohort study.BMJ (Clinical research ed.) · 2017Article
- Risk of Coronary Heart Events Based on Rose Angina Questionnaire and ECG Besides Diabetes and Other Metabolic Risk Factors: Results of a 10-Year Follow-up in Tehran Lipid and Glucose Study.International journal of endocrinology and metabolism · 2017Article
- Breviscapine Injection Improves the Therapeutic Effect of Western Medicine on Angina Pectoris Patients.PloS one · 2015Article
- An exploration of the dynamic longitudinal relationship between mental health and alcohol consumption: a prospective cohort study.BMC medicine · 2014Article
- Hypertension education and adherence in South Africa: a cost-effectiveness analysis of community health workers.BMC public health · 2014Article
- Prognosis research strategy (PROGRESS) 1: a framework for researching clinical outcomes.BMJ (Clinical research ed.) · 2013Article
- Symptom clusters and health-related quality of life in people with chronic stable angina.Journal of advanced nursing · 2011Article
- Impact of an occupational health promotion program on subsequent illness and mortality experience.International archives of occupational and environmental health · 2010Article
- Patients' descriptions of angina symptoms: a qualitative study of primary care patients.The British journal of general practice : the journal of the Royal College of General Practitioners · 2010Article
- Recent advances in the management of chronic stable angina I: approach to the patient, diagnosis, pathophysiology, risk stratification, and gender disparities.Vascular health and risk management · 2010Review
- The conundrum of detecting stable angina pectoris in the community setting.Nature reviews. Cardiology · 2010Review
- Five year prognosis in patients with angina identified in primary care: incident cohort study.BMJ (Clinical research ed.) · 2009Article
Corrections and comments
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveTo investigate the prognosis of angina among people with and without diagnosis by a doctor and an abnormal cardiovascular test result.
designProspective cohort study with a median follow up of 11 years.
setting20 civil service departments originally located in London.
participants10 308 civil servants aged 35-55 years at baseline.
main outcome measuresRecurrent reports of angina; quality of life (SF-36 physical functioning); non-fatal myocardial infarction; death from any cause (n = 344).
results1158 (11.4%) participants developed angina, and 813 (70%) had no evidence of diagnosis by a doctor at the time of the initial report. Participants without a diagnosis had an increased risk of impaired physical functioning (age and sex adjusted odds ratio of 2.36 (95% confidence interval 1.91 to 2.90)) compared with those who had neither angina nor myocardial infarction throughout follow up. Among reported cases of angina without a diagnosis, the 15.5% with an abnormality on a study electrocardiogram had an increased risk of death (hazard ratio 2.37 (1.16 to 4.87)). These effects were similar in magnitude to those in participants with a diagnosis of angina.
conclusionUndiagnosed angina was common and had an adverse impact on prognosis comparable to that of diagnosed angina, particularly among people with electrocardiographic abnormalities. Efforts to improve prognosis among people with angina should take account of this submerged clinical iceberg.
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