ArticleWorld journal of gastroenterology2003
Prognostic factors in 165 elderly colorectal cancer patients.
Article in World journal of gastroenterology, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Clinical characteristics and prognosis of 196 Chinese patients with colon cancer.Frontiers in surgery · 2022Article
- Predicting Colorectal Cancer Recurrence and Patient Survival Using Supervised Machine Learning Approach: A South African Population-Based Study.Frontiers in public health · 2021Article
- Comparison of Basic and Ensemble Data Mining Methods in Predicting 5-Year Survival of Colorectal Cancer Patients.Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH · 2017Article
- Clinicopathological characteristics and long-term outcomes of colorectal cancer in elderly Chinese patients undergoing potentially curative surgery.Surgery today · 2014Article
- Prognostic and survival analysis of 837 Chinese colorectal cancer patients.World journal of gastroenterology · 2013Article
- Improving the performance of risk-adjusted mortality modeling for colorectal cancer surgery by combining claims data and clinical data.Journal of preventive medicine and public health = Yebang Uihakhoe chi · 2013Article
- The Estimation of Survival Function for Colon Cancer Data in Tehran Using Non-parametric Bayesian Model.Iranian journal of cancer prevention · 2013Article
- An overview of colorectal cancer survival rates and prognosis in Asia.World journal of gastrointestinal oncology · 2012Article
- Impact of age-related comorbidity on results of colorectal cancer surgery.World journal of gastroenterology · 2009Article
- Significance of the immunohistochemical detection of lymph node micrometastases in stage II colorectal carcinoma.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2006Article
- Implications of CEA and p53 overexpression in the poor prognosis of colorectal cancer.Medical oncology (Northwood, London, England) · 2006Article
- Colorectal cancer treatment and follow-up in the elderly: an inexplicably different approach.International surgeryArticle
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3 authors.
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Abstract
aimTo analyse the prognostic factors in 165 colorectal patients aged > or =70.
methodsOne hundred and sixty-five elderly patients with colorectal cancer diagnosed by histology were entered into the retrospective study between 1994 and 2001. Patients were given optimal operation alone, chemotherapy after operation, or chemotherapy alone according to tumor stage, histology, physical strength, and co-morbid problems. Survival rate was calculated by Kaplan-Meier method, and compared with meaningful variances by Log-rank method. Prognostic factors were analyzed by Cox regression.
resultsThe 1,2,3,4,5 year survival rate (all-cause mortality) was 87.76 %, 65.96%, 52.05%, 42.77 %, 40.51%, respectively. The mean survival time was 41.89+/-2.33 months (95% CI: 37.33-46.45 months), and the median survival time was 37 months. Univariate analysis showed that factors such as age, nodal metastasis, treatment method, Duke's stage, gross findings, kind of histology, and degree of differentiation had influences on the survival rate. Multivariate analysis showed that factors such as treatment method, Duke's stage, kind of histology and degree of differentiation were independent prognostic factors.
conclusionThis study suggests that the prognosis of elderly colorectal cancer patients is influenced by several factors. Most of elderly patients can endure surgery and/or chemotherapy, and have a long-time survival and good quality of life.
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