Evidence map›Paper›PMID 14562131›Full record

ArticleInternational journal of impotence research2003

Long-term efficacy and compliance of intracorporeal (IC) injection for erectile dysfunction following radical prostatectomy: SHIM (IIEF-5) analysis.

R Raina, M M Lakin, M Thukral, A Agarwal, S Ausmundson, D K Montague, E Klein, C D Zippe

Abstract read
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In one paragraph

Article in International journal of impotence research, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 3 pooled it
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 3 syntheses or guidelines pooled it, 74 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Penile prosthesis implantation: a bibliometric-based visualization study.International journal of impotence research · 2025
    Article
  7. Article
  8. Review
  9. Sexual Dysfunction and Intimacy for Ostomates.Clinics in colon and rectal surgery · 2017
    Review
  10. Review
  11. Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. Review
  17. Erectile preservation following radical prostatectomy.Therapeutic advances in urology · 2011
    Article
  18. Penile rehabilitation following treatment for prostate cancer: an analysis of the current state of the art.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2009
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

R RainaGlickman Urological Institute, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.
M M Lakin
M Thukral
A Agarwal
S Ausmundson
D K Montague
E Klein
C D Zippe
Cleveland Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Baseline and follow-up data from 102 patients using intracorporeal (IC) injection for erectile dysfunction (ED) following RP were retrospectively collected. We compared baseline International Index for Erectile Function (IIEF) questionnaires with the abridged IIEF-5 questionnaires, referred to as the Sexual Health Inventory of Men (SHIM) to determine drug efficacy. The mean presurgery SHIM score was 21.75+/-5.23, which decreased to 4.23+/-3.48 after surgery and increased to 19.46+/-8.78 post-treatment. Overall, 68% (69/102) of patients achieved and maintained erections sufficient for sexual intercourse and 48% (49/102) of patients continued long-term therapy with a mean use of 3.7+/-1.9 y. In all, 52% (53/102) patients discontinued IC therapy. However when excluding patients who switched to oral therapy, had loss of partner or return of normal erections; the compliance to IC injections was 70.6% (71/102). There was no difference in the SHIM analysis between the nerve sparing (NS) and the non-NS or between the types of medications used. IC injections can provide excellent long-term efficacy and compliance in up to 70% of the patients. This study suggests that IC injections are an excellent salvage option in NS patients who fail oral therapy and a first option in patients with non-NS procedures.

Indexed as

ProstatectomyAgedAlprostadilAntihypertensive AgentsDrug Therapy, CombinationErectile DysfunctionFollow-Up StudiesHumansMaleMiddle AgedPapaverinePatient CompliancePenisPhentolamineRetrospective StudiesSalvage TherapyAlprostadilAntihypertensive AgentsPapaverinePhentolamineVasodilator Agents

Identifiers

PMID14562131
OpenAlexW2078842830

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.