Evidence map›Paper›PMID 14561696›Full record

ArticleThe Journal of clinical investigation2003

What brings pericytes to tumor vessels?

Rakesh K Jain, Michael F Booth

Open access · greenAbstract readComment
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of clinical investigation, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers.

0numbers the graph read from it
0cells of the map it votes in
66citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

66 citing papers in PubMed, 143 citations in OpenAlex.

  1. Trial
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  11. Pericytes Elicit Resistance to Vemurafenib and Sorafenib Therapy in Thyroid Carcinoma via the TSP-1/TGFβ1 Axis.Clinical cancer research : an official journal of the American Association for Cancer Research · 2018
    Article
  12. Review
  13. Article
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  15. Article
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  19. Medical treatment for gastro-entero-pancreatic neuroendocrine tumours.World journal of gastrointestinal oncology · 2016
    Review
  20. Review

6 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Rakesh K JainEdwin L. Steele Laboratory, Department of Radiation Oncology, Boston, Massachusetts 02114, USA. jain@steele.mgh.harvard.edu
Michael F Booth
Harvard University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Paracrine signaling via platelet-derived growth factor B (PDGFB), expressed by endothelial cells, and its receptor PDGFR-beta, expressed by pericytes, plays a central role in blood vessel maturation. A new study (see the related article beginning on page 1142) reveals that it is not just the presence of PDGFB, but how it is presented to pericytes, that determines the quality of the endothelium-pericyte interaction.

Indexed as

AnimalsCell MovementEndothelium, VascularMiceNeoplasms, ExperimentalNeovascularization, PathologicPericytesProto-Oncogene Proteins c-sisReceptor, Platelet-Derived Growth Factor betaVascular Endothelial Growth Factor AProto-Oncogene Proteins c-sisReceptor, Platelet-Derived Growth Factor betaVascular Endothelial Growth Factor A

Identifiers

PMID14561696
PMCPMC213497
OpenAlexW1971076526

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.