ArticleLearning & memory (Cold Spring Harbor, N.Y.)
Developmental changes in eyeblink conditioning and neuronal activity in the pontine nuclei.
Article in Learning & memory (Cold Spring Harbor, N.Y.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
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Who cites it
31 citing papers in PubMed, 49 citations in OpenAlex.
- A transient feature of the inferior olive supports the development of cerebellar internal models.bioRxiv : the preprint server for biology · 2025Article
- Developmentally Unique Cerebellar Processing Prioritizes Self- over Other-Generated Movements.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Developmentally unique cerebellar processing prioritizes self-over other-generated movements.bioRxiv : the preprint server for biology · 2024Article
- Abnormal eyeblink conditioning is an early marker of cerebellar dysfunction in preclinical SCA3 mutation carriers.Experimental brain research · 2019Article
- Medial Auditory Thalamus Is Necessary for Expression of Auditory Trace Eyelid Conditioning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
- A neural model of normal and abnormal learning and memory consolidation: adaptively timed conditioning, hippocampus, amnesia, neurotrophins, and consciousness.Cognitive, affective & behavioral neuroscience · 2017Article
- Sensory system development influences the ontogeny of eyeblink conditioning.Developmental psychobiology · 2014Article
- Awareness is essential for differential delay eyeblink conditioning with soft-tone but not loud-tone conditioned stimuli.Neuroscience bulletin · 2014Article
- Prefrontal control of cerebellum-dependent associative motor learning.Cerebellum (London, England) · 2014Article
- Article
- Developmental changes in medial auditory thalamic contributions to associative motor learning.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012Article
- Multiple sites of extinction for a single learned response.Journal of neurophysiology · 2012Article
- Stimulus-dependent state transition between synchronized oscillation and randomly repetitive burst in a model cerebellar granular layer.PLoS computational biology · 2011Article
- Neuronal correlates of cross-modal transfer in the cerebellum and pontine nuclei.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2011Article
- Neural circuitry and plasticity mechanisms underlying delay eyeblink conditioning.Learning & memory (Cold Spring Harbor, N.Y.) · 2011Review
- Temporal patterns of inputs to cerebellum necessary and sufficient for trace eyelid conditioning.Journal of neurophysiology · 2010Article
- Medial auditory thalamic input to the lateral pontine nuclei is necessary for auditory eyeblink conditioning.Neurobiology of learning and memory · 2010Article
- Computational models of timing mechanisms in the cerebellar granular layer.Cerebellum (London, England) · 2009Review
- Dynamics of fast and slow inhibition from cerebellar golgi cells allow flexible control of synaptic integration.Neuron · 2009Article
- Interactions between prefrontal cortex and cerebellum revealed by trace eyelid conditioning.Learning & memory (Cold Spring Harbor, N.Y.) · 2009Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Neuronal activity was recorded in the pontine nuclei of developing rats during eyeblink conditioning on postnatal days 17-18 (P17-P18) or P24-P25. A pretraining session consisted of unpaired presentations of a 300-msec tone conditioned stimulus (CS) and a 10-msec periorbital shock unconditioned stimulus (US). Five paired training sessions followed the unpaired session, consisting of 100 trials of the CS paired with the US. The rats trained on P24-P25 exhibited significantly more conditioned responses (CRs) than the rats trained on P17-P18, although both groups produced CRs by the end of training. Ontogenetic increases in pre-CS and stimulus-elicited activity in the pontine nuclei were observed during the pretraining session and after paired training. The activity of pontine units was greater on trials with CRs relative to trials without CRs in rats trained on P24-P25, but almost no CR-related modulation was observed in the pontine units of rats trained on P17-P18. The findings indicate that pontine neuronal responses to the CS and modulation of pontine activity by the cerebellum and red nucleus undergo substantial postnatal maturation. The developmental changes in pontine neuronal activity might play a significant role in the ontogeny of eyeblink conditioning.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.