ReviewClinical microbiology reviews2003
Laboratory diagnosis of amebiasis.
Review in Clinical microbiology reviews, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 147 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
147 citing papers in PubMed, 4 syntheses or guidelines pooled it, 483 citations in OpenAlex.
- Antiamoebic drugs for treating amoebic colitis.The Cochrane database of systematic reviews · 2019Pooled it
- A Guide to Utilization of the Microbiology Laboratory for Diagnosis of Infectious Diseases: 2018 Update by the Infectious Diseases Society of America and the American Society for Microbiology.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018Guideline
- Colonoscopic diagnosis of amebiasis: a case series and systematic review.International journal of colorectal disease · 2015Pooled it
- A guide to utilization of the microbiology laboratory for diagnosis of infectious diseases: 2013 recommendations by the Infectious Diseases Society of America (IDSA) and the American Society for Microbiology (ASM)(a).Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2013Guideline
- Automated detection and classification of intestinal protozoan cysts using a nuclei structure-based deep learning framework for epidemiological surveillance.Parasite epidemiology and control · 2026Article
- Gastrointestinal Parasites of Domestic Ducks (Anas platyrhynchos domesticus) in Kathmandu, Nepal.Veterinary medicine and science · 2026Article
- Current and emerging molecular diagnostic approaches in the detection of human parasites.Parasitology research · 2026Review
- Extraintestinal Entamoeba moshkovskii Infection, Eastern India.Emerging infectious diseases · 2026Article
- Assessment of three major intestinal protozoan infections in Kermanshah, Iran: a pre- and post-COVID-19 study.BMC research notes · 2026Article
- Early Clinical Response of a Large Amebic Liver Abscess to Eravacycline Prior to Metronidazole Initiation: A Case Report.Case reports in infectious diseases · 2026Article
- Henoch-Schönlein Purpura Triggered by Amebiasis in a Young Female Child: A Case Report and Literature Review.Cureus · 2025Article
- Article
- Genotypic characterization ofFood and waterborne parasitology · 2025Article
- Intestinal protozoa infections and associated factors among diarrheal under-five children in Borena district, central Ethiopia.Parasite epidemiology and control · 2025Article
- Decision tree-based learning and laboratory data mining: an efficient approach to amebiasis testing.Parasites & vectors · 2025Article
- Entamoeba histolytica in Different Water Sources of Niğde Province of Turkey.Acta parasitologica · 2024Article
- Occult Amebiasis among Pediatric with Enterocolitis in National Referral Hospital in Indonesia.Infection & chemotherapy · 2024Article
- Amebic liver abscess: An update.World journal of hepatology · 2024Review
- Development of nucleic acid lateral flow immunoassay for molecular detection of Entamoeba moshkovskii and Entamoeba dispar in stool samples.Scientific reports · 2024Article
- Amoebic Liver Abscess: Potential Application of New Diagnostic Techniques for an Old Pathogen.Infectious diseases and therapy · 2024Article
87 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 2 countries.
Funding
Abstract
The detection of Entamoeba histolytica, the causative agent of amebiasis, is an important goal of the clinical microbiology laboratory. To assess the scope of E. histolytica infection, it is necessary to utilize accurate diagnostic tools. As more is discovered about the molecular and cell biology of E. histolytica, there is great potential for further understanding the pathogenesis of amebiasis. Molecular biology-based diagnosis may become the technique of choice in the future because establishment of these protozoa in culture is still not a routine clinical laboratory process. In all cases, combination of serologic tests with detection of the parasite (by antigen detection or PCR) offers the best approach to diagnosis, while PCR techniques remain impractical in many developing country settings. The detection of amebic markers in serum in patients with amebic colitis and liver abscess appears promising but is still only a research tool. On the other hand, stool antigen detection tests offer a practical, sensitive, and specific way for the clinical laboratory to detect intestinal E. histolytica. All the current tests suffer from the fact that the antigens detected are denatured by fixation of the stool specimen, limiting testing to fresh or frozen samples.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.