ArticleNucleic acids research1992
Oligonucleotide probes detect splicing variants in situ in Drosophila embryos.
Article in Nucleic acids research, 1992. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
10 citing papers in PubMed, 17 citations in OpenAlex.
- Combinatorial Gene Regulatory Functions Underlie Ultraconserved Elements in Drosophila.Molecular biology and evolution · 2016Article
- The RNA-binding protein ELAV regulates Hox RNA processing, expression and function within the Drosophila nervous system.Development (Cambridge, England) · 2014Article
- A FRET-based assay for characterization of alternative splicing events using peptide nucleic acid fluorescence in situ hybridization.Nucleic acids research · 2009Article
- In situ detection of non-polyadenylated RNA molecules using Turtle Probes and target primed rolling circle PRINS.BMC biotechnology · 2007Article
- RNA molecules lighting up under the microscope.Histochemistry and cell biology · 1996Review
- Stage, tissue, and cell specific distribution of alternative Ultrabithorax mRNAs and protein isoforms in the Drosophila embryo.Roux's archives of developmental biology : the official organ of the EDBO · 1996Article
- Molecular characterization of the zerknüllt region of the Antennapedia complex of D. subobscura.Chromosoma · 1995Article
- Article
- Evolutionary conservation of the structure and expression of alternatively spliced Ultrabithorax isoforms from Drosophila.Genetics · 1994Article
- Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 2 countries.
Funding
Abstract
We describe a method for the in situ detection of specific splicing variants. The method is based on the use of antisense oligonucleotides designed to span splice junctions labelled with digoxigenin by terminal transferase tailing. We find that the spatial patterns of Ubx splicing variants Ia and IIa are similar in early embryos, but differ in late embryos. Variant IVa is only detected in the CNS (ps6) at stages 16 and 17. We also present evidence indicating that the first splicing event is cotranscriptional.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.