ReviewEpilepsy & behavior : E&B2003
Epilepsy and cognition.
Review in Epilepsy & behavior : E&B, 2003. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05954182 (Cognitive Enhancement Intervention for Creating a Healthy L.I.F.E), which is not on this map. Cited by 58 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Cognitive Enhancement Intervention for Creating a Healthy L.I.F.E (Lifestyle Interventions for Epilepsy)
Who cites it
58 citing papers in PubMed, 4 syntheses or guidelines pooled it, 299 citations in OpenAlex.
- Exploring the Smoking-Epilepsy Nexus: a systematic review and meta-analysis of observational studies : Smoking and epilepsy.BMC medicine · 2024Pooled it
- The relationship between physical activity and cognitive function in people with epilepsy: A systematic review.Epilepsy & behavior : E&B · 2023Pooled it
- The P300 Event-Related Potential Component and Cognitive Impairment in Epilepsy: A Systematic Review and Meta-analysis.Frontiers in neurology · 2019Pooled it
- Memory Rehabilitation in Patients with Epilepsy: a Systematic Review.Neuropsychology review · 2018Pooled it
- Quality of life during usual epilepsy care for anxiety or depression symptoms: Secondary patient-reported outcomes in a randomized trial of remote assessment methods.Epilepsy research · 2024Trial
- Brain's compensatory response to drug-induced cognitive impairment.Journal of clinical and experimental neuropsychology · 2018Trial
- The effect of topiramate plasma concentration on linguistic behavior, verbal recall and working memory.Epilepsy & behavior : E&B · 2012Trial
- An Online Epilepsy Self-Management Tool for Patients With Epilepsy: A Formative Usability Study.JMIR human factors · 2026Article
- Executive dysfunction and employment in epilepsy.Epilepsia · 2026Article
- Geographic Disparities in People with Epilepsy: Differences in Self-Efficacy and Quality of Life.Journal of epilepsy research · 2026Article
- Neurobehavioral Signatures of Epileptogenesis: Molecular Programs, Trait-like Phenotypes, and Translational Biomarkers Beyond Seizures.International journal of molecular sciences · 2026Review
- Neurocognitive and neurobiological features of early-stage, unmedicated patients with bipolar disorder.Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) · 2025Article
- Emotional intelligence in children with epilepsy.IBRO neuroscience reports · 2024Article
- Novelty preference assessed by eye tracking: A sensitive measure of impaired recognition memory in epilepsy.Epilepsy & behavior : E&B · 2024Article
- Neuromorphometric associations with mood, cognition, and self-reported exercise levels in epilepsy and healthy individuals.Epilepsy & behavior reports · 2024Article
- Role of Pyroptosis, a Pro-inflammatory Programmed Cell Death, in Epilepsy.Cellular and molecular neurobiology · 2023Review
- Pulsed Focused Ultrasound Reduces Hippocampal Volume Loss and Improves Behavioral Performance in the Kainic Acid Rat Model of Epilepsy.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2023Article
- Urinary Neurotransmitter Patterns Are Altered in Canine Epilepsy.Frontiers in veterinary science · 2022Article
- Neurocognitive Effects of Antiseizure Medications in Children and Adolescents with Epilepsy.Paediatric drugs · 2021Review
- A Platform for Cognitive Monitoring of Neurosurgical Patients During Hospitalization.Frontiers in human neuroscience · 2021Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Patients with epilepsy are more prone to cognitive and behavioral deficits. Epilepsy per se may induce or exacerbate an underlying cognitive impairment, a variety of factors contribute to such deficits, i.e., underlying neuropathology, seizure type, age of onset, psychosocial problems, and treatment side effects. Epilepsy treatment may offset the cognitive and behavioral impairments by stopping or decreasing the seizures, but it may also induce untoward effects on cognition and behavior. The neurocognitive burden of epilepsy may even start through in utero exposure to medications. Epilepsy surgery can also induce certain cognitive deficits, although in most cases this can be minimized. Clinicians should consider cognitive side effect profiles of antiepileptic medications, particularly in extreme age groups. While no effective treatments are available for cognitive and behavioral impairments in epilepsy, comprehensive pretreatment evaluation and meticulous selection of antiepileptic drugs or surgical approach may minimize such untoward effects.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.